Long-range chromosomal interactions increase and mark repressed gene expression during adipogenesis

Long-range chromosomal interactions increase and mark repressed gene expression during adipogenesis

Obesity perturbs central functions of human adipose tissue, centred on differentiation of preadipocytes to adipocytes, i.e., adipogenesis. The large environmental component of obesity makes it important to elucidate epigenetic regulatory factors impacting adipogenesis. Promoter Capture Hi-C (pCHi-C)...

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Bibliographic Details
Main Authors: Kristina M. Garske, Caroline Comenho, David Z. Pan, Marcus Alvarez, Karen Mohlke, Markku Laakso, Kirsi H. Pietiläinen, Päivi Pajukanta
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Epigenetics
Subjects:
adipogenesis
obesity
chromosomal interactions
Online Access:http://dx.doi.org/10.1080/15592294.2022.2088145

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