Focal Lesions of the Liver and Radiomics: What Do We Know?

Despite differences in pathological analysis, focal liver lesions are not always distinguishable in contrast-enhanced magnetic resonance imaging (MRI), contrast-enhanced computed tomography (CT), and positron emission tomography (PET). This issue can cause problems of differential diagnosis, treatme...

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Main Authors: Matilde Anichini, Antonio Galluzzo, Ginevra Danti, Giulia Grazzini, Silvia Pradella, Francesca Treballi, Eleonora Bicci
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/13/15/2591
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author Matilde Anichini
Antonio Galluzzo
Ginevra Danti
Giulia Grazzini
Silvia Pradella
Francesca Treballi
Eleonora Bicci
author_facet Matilde Anichini
Antonio Galluzzo
Ginevra Danti
Giulia Grazzini
Silvia Pradella
Francesca Treballi
Eleonora Bicci
author_sort Matilde Anichini
collection DOAJ
description Despite differences in pathological analysis, focal liver lesions are not always distinguishable in contrast-enhanced magnetic resonance imaging (MRI), contrast-enhanced computed tomography (CT), and positron emission tomography (PET). This issue can cause problems of differential diagnosis, treatment, and follow-up, especially in patients affected by HBV/HCV chronic liver disease or fatty liver disease. Radiomics is an innovative imaging approach that extracts and analyzes non-visible quantitative imaging features, supporting the radiologist in the most challenging differential diagnosis when the best-known methods are not conclusive. The purpose of this review is to evaluate the most significant CT and MRI texture features, which can discriminate between the main benign and malignant focal liver lesions and can be helpful to predict the response to pharmacological or surgical therapy and the patient’s prognosis.
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spelling doaj.art-8b05dcc5fac141d3a3128383aff811b52023-11-18T22:47:33ZengMDPI AGDiagnostics2075-44182023-08-011315259110.3390/diagnostics13152591Focal Lesions of the Liver and Radiomics: What Do We Know?Matilde Anichini0Antonio Galluzzo1Ginevra Danti2Giulia Grazzini3Silvia Pradella4Francesca Treballi5Eleonora Bicci6Department of Radiology, Careggi University Hospital, Largo Brambilla 3, 50134 Florence, ItalyDepartment of Radiology, Careggi University Hospital, Largo Brambilla 3, 50134 Florence, ItalyDepartment of Radiology, Careggi University Hospital, Largo Brambilla 3, 50134 Florence, ItalyDepartment of Radiology, Careggi University Hospital, Largo Brambilla 3, 50134 Florence, ItalyDepartment of Radiology, Careggi University Hospital, Largo Brambilla 3, 50134 Florence, ItalyDepartment of Radiology, Careggi University Hospital, Largo Brambilla 3, 50134 Florence, ItalyDepartment of Radiology, Careggi University Hospital, Largo Brambilla 3, 50134 Florence, ItalyDespite differences in pathological analysis, focal liver lesions are not always distinguishable in contrast-enhanced magnetic resonance imaging (MRI), contrast-enhanced computed tomography (CT), and positron emission tomography (PET). This issue can cause problems of differential diagnosis, treatment, and follow-up, especially in patients affected by HBV/HCV chronic liver disease or fatty liver disease. Radiomics is an innovative imaging approach that extracts and analyzes non-visible quantitative imaging features, supporting the radiologist in the most challenging differential diagnosis when the best-known methods are not conclusive. The purpose of this review is to evaluate the most significant CT and MRI texture features, which can discriminate between the main benign and malignant focal liver lesions and can be helpful to predict the response to pharmacological or surgical therapy and the patient’s prognosis.https://www.mdpi.com/2075-4418/13/15/2591livercontrast-enhanced computed tomography (CT)contrast-enhanced magnetic resonance (MRI)radiomicstexture features
spellingShingle Matilde Anichini
Antonio Galluzzo
Ginevra Danti
Giulia Grazzini
Silvia Pradella
Francesca Treballi
Eleonora Bicci
Focal Lesions of the Liver and Radiomics: What Do We Know?
Diagnostics
liver
contrast-enhanced computed tomography (CT)
contrast-enhanced magnetic resonance (MRI)
radiomics
texture features
title Focal Lesions of the Liver and Radiomics: What Do We Know?
title_full Focal Lesions of the Liver and Radiomics: What Do We Know?
title_fullStr Focal Lesions of the Liver and Radiomics: What Do We Know?
title_full_unstemmed Focal Lesions of the Liver and Radiomics: What Do We Know?
title_short Focal Lesions of the Liver and Radiomics: What Do We Know?
title_sort focal lesions of the liver and radiomics what do we know
topic liver
contrast-enhanced computed tomography (CT)
contrast-enhanced magnetic resonance (MRI)
radiomics
texture features
url https://www.mdpi.com/2075-4418/13/15/2591
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