Clinical Performance of Diagnostic Methods in Third Molar Teeth with Early Occlusal Caries
The aim of this study was to compare the diagnostic performance of clinical visual examination (ICDAS II), digital periapical radiography (PR), near infrared light transillumination (NIR-LT), and laser fluorescence (LF) to microcomputed tomography (Micro-CT) which is the reference standard for the d...
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| Format: | Article |
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MDPI AG
2023-01-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/13/2/284 |
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| author | Nazan Kocak-Topbas Kıvanç Kamburoğlu Ayşe Tuğba Ertürk-Avunduk Mehmet Ozgur Ozemre Nejlan Eratam Esra Ece Çakmak |
| author_facet | Nazan Kocak-Topbas Kıvanç Kamburoğlu Ayşe Tuğba Ertürk-Avunduk Mehmet Ozgur Ozemre Nejlan Eratam Esra Ece Çakmak |
| author_sort | Nazan Kocak-Topbas |
| collection | DOAJ |
| description | The aim of this study was to compare the diagnostic performance of clinical visual examination (ICDAS II), digital periapical radiography (PR), near infrared light transillumination (NIR-LT), and laser fluorescence (LF) to microcomputed tomography (Micro-CT) which is the reference standard for the detection of non-cavitated occlusal enamel and dentin caries in third molar teeth. Potential participants were consecutively recruited. In this prospective study, 101 third molars of 101 patients were examined; the molars had non-cavitated occlusal caries which required extraction. ICDAS II, PR, NIR-LT and LF examinations were carried out by two blinded examiners. Reference standard was determined by micro-CT imaging seven days after extraction. Accuracy rate, sensitivity, specificity, predictive values and areas under receiver operating characteristic (ROC) curves (Az) were statistically analyzed. Nonparametric variables were subjected to the Kruskal–Wallis Test. Significance level was set as <i>p</i> < 0.05. NIR-LT had the highest sensitivity (99.67–99.67%) and accuracy (78.22–77.23%) for the determination of occlusal enamel caries according to examiners 1 and 2, respectively. LF method had the highest sensitivity (70.83–54.17%) and accuracy (66.34–59.41%) for determining occlusal dentin caries according to examiners 1 and 2, respectively. The ROC curve (Az) value ranged between 0.524 and 0.726 for the different methods tested. Most effective methods for the diagnosis of occlusal enamel and dentin caries were determined to be NIR-LT and LF pen methods, respectively. The present prospective clinical study showed that NIR-LT and LF-Pen were a reliable modality for the detection of occlusal enamel and dentin caries without ionizing radiation. |
| first_indexed | 2024-03-09T13:02:55Z |
| format | Article |
| id | doaj.art-8b070179ba48487081b2d2c1d797af76 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-09T13:02:55Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-8b070179ba48487081b2d2c1d797af762023-11-30T21:52:34ZengMDPI AGDiagnostics2075-44182023-01-0113228410.3390/diagnostics13020284Clinical Performance of Diagnostic Methods in Third Molar Teeth with Early Occlusal CariesNazan Kocak-Topbas0Kıvanç Kamburoğlu1Ayşe Tuğba Ertürk-Avunduk2Mehmet Ozgur Ozemre3Nejlan Eratam4Esra Ece Çakmak5Department of Dentomaxillofacial Radiology, Faculty of Dentistry, Mersin University, Mersin 33343, TurkeyDepartment of Dentomaxillofacial Radiology, Faculty of Dentistry, Ankara University, Ankara 06110, TurkeyDepartment of Restorative Dentistry, Faculty of Dentistry, Mersin University, Mersin 33343, TurkeyDepartment of Dentomaxillofacial Radiology, Faculty of Dentistry, Mersin University, Mersin 33343, TurkeyDepartment of Dentomaxillofacial Radiology, Faculty of Dentistry, Ankara University, Ankara 06110, TurkeyDepartment of Dentomaxillofacial Radiology, Faculty of Dentistry, Ankara University, Ankara 06110, TurkeyThe aim of this study was to compare the diagnostic performance of clinical visual examination (ICDAS II), digital periapical radiography (PR), near infrared light transillumination (NIR-LT), and laser fluorescence (LF) to microcomputed tomography (Micro-CT) which is the reference standard for the detection of non-cavitated occlusal enamel and dentin caries in third molar teeth. Potential participants were consecutively recruited. In this prospective study, 101 third molars of 101 patients were examined; the molars had non-cavitated occlusal caries which required extraction. ICDAS II, PR, NIR-LT and LF examinations were carried out by two blinded examiners. Reference standard was determined by micro-CT imaging seven days after extraction. Accuracy rate, sensitivity, specificity, predictive values and areas under receiver operating characteristic (ROC) curves (Az) were statistically analyzed. Nonparametric variables were subjected to the Kruskal–Wallis Test. Significance level was set as <i>p</i> < 0.05. NIR-LT had the highest sensitivity (99.67–99.67%) and accuracy (78.22–77.23%) for the determination of occlusal enamel caries according to examiners 1 and 2, respectively. LF method had the highest sensitivity (70.83–54.17%) and accuracy (66.34–59.41%) for determining occlusal dentin caries according to examiners 1 and 2, respectively. The ROC curve (Az) value ranged between 0.524 and 0.726 for the different methods tested. Most effective methods for the diagnosis of occlusal enamel and dentin caries were determined to be NIR-LT and LF pen methods, respectively. The present prospective clinical study showed that NIR-LT and LF-Pen were a reliable modality for the detection of occlusal enamel and dentin caries without ionizing radiation.https://www.mdpi.com/2075-4418/13/2/284laser fluorescencenear-infrared light transilluminationMicro-CTnon-cavitated occlusal cariesvisual analog scale |
| spellingShingle | Nazan Kocak-Topbas Kıvanç Kamburoğlu Ayşe Tuğba Ertürk-Avunduk Mehmet Ozgur Ozemre Nejlan Eratam Esra Ece Çakmak Clinical Performance of Diagnostic Methods in Third Molar Teeth with Early Occlusal Caries Diagnostics laser fluorescence near-infrared light transillumination Micro-CT non-cavitated occlusal caries visual analog scale |
| title | Clinical Performance of Diagnostic Methods in Third Molar Teeth with Early Occlusal Caries |
| title_full | Clinical Performance of Diagnostic Methods in Third Molar Teeth with Early Occlusal Caries |
| title_fullStr | Clinical Performance of Diagnostic Methods in Third Molar Teeth with Early Occlusal Caries |
| title_full_unstemmed | Clinical Performance of Diagnostic Methods in Third Molar Teeth with Early Occlusal Caries |
| title_short | Clinical Performance of Diagnostic Methods in Third Molar Teeth with Early Occlusal Caries |
| title_sort | clinical performance of diagnostic methods in third molar teeth with early occlusal caries |
| topic | laser fluorescence near-infrared light transillumination Micro-CT non-cavitated occlusal caries visual analog scale |
| url | https://www.mdpi.com/2075-4418/13/2/284 |
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