Postsynaptic histamine H3 receptors in ventral basal forebrain cholinergic neurons modulate contextual fear memory

Postsynaptic histamine H3 receptors in ventral basal forebrain cholinergic neurons modulate contextual fear memory

Summary: Overly strong fear memories can cause pathological conditions. Histamine H3 receptor (H3R) has been viewed as an optimal drug target for CNS disorders, but its role in fear memory remains elusive. We find that a selective deficit of H3R in cholinergic neurons, but not in glutamatergic neuro...

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Bibliographic Details
Main Authors: Yanrong Zheng, Lishi Fan, Zhuowen Fang, Zonghan Liu, Jiahui Chen, Xiangnan Zhang, Yi Wang, Yan Zhang, Lei Jiang, Zhong Chen, Weiwei Hu
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Cell Reports
Subjects:
CP: Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723010847

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