Transport of the pituitary adenylate cyclase-activating polypeptide across the blood-brain barrier: implications for migraine

Transport of the pituitary adenylate cyclase-activating polypeptide across the blood-brain barrier: implications for migraine

Abstract Background Pituitary adenylate cyclase-activating polypeptide (PACAP) is widely distributed in the nervous system and is involved in migraine pathophysiology. Understanding the function of the blood-brain barrier (BBB) in relation to PACAP is important to the understand the mechanisms behin...

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Bibliographic Details
Main Authors: Faisal Mohammad Amin, Henrik Winther Schytz
Format: Article
Language:English
Published: BMC 2018-05-01
Series:The Journal of Headache and Pain
Subjects:
Migraine
PACAP
Blood-brain barrier
Online Access:http://link.springer.com/article/10.1186/s10194-018-0861-3

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