PHNQ from <i>Evechinus chloroticus</i> Sea Urchin Supplemented with Calcium Promotes Mineralization in Saos-2 Human Bone Cell Line

PHNQ from <i>Evechinus chloroticus</i> Sea Urchin Supplemented with Calcium Promotes Mineralization in Saos-2 Human Bone Cell Line

Polyhydroxylated naphthoquinones (PHNQs), known as spinochromes that can be extracted from sea urchins, are bioactive compounds reported to have medicinal properties and antioxidant activity. The MTT (3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) cell viability assay showed that pure...

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Bibliographic Details
Main Authors: Yakun Hou, Alan Carne, Michelle McConnell, Sonya Mros, Elena A. Vasileva, Natalia P. Mishchenko, Keegan Burrow, Ke Wang, Adnan A. Bekhit, Alaa El-Din A. Bekhit
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Marine Drugs
Subjects:
PHNQ
sea urchin
spinochrome
cytotoxicity
Saos-2 cells
mineralized nodule formation
Online Access:https://www.mdpi.com/1660-3397/18/7/373

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