An Integrated In Silico and In Vitro Assays of Dipeptidyl Peptidase-4 and α-Glucosidase Inhibition by Stellasterol from <i>Ganoderma australe</i>

An Integrated In Silico and In Vitro Assays of Dipeptidyl Peptidase-4 and α-Glucosidase Inhibition by Stellasterol from <i>Ganoderma australe</i>

Background: <i>Ganoderma</i> fungus is rich in terpenoids. These compounds are known for their anti-hyperglycemic activities. However, the study of terpenoids as the secondary metabolite from <i>Ganoderma</i> as a dipeptidyl peptidase-4 (DPP-4) inhibitor remains unexplored. I...

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Bibliographic Details
Main Authors: Krisyanti Budipramana, Junaidin Junaidin, Komar Ruslan Wirasutisna, Yanatra Budi Pramana, Sukrasno Sukrasno
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Scientia Pharmaceutica
Subjects:
α-glucosidase inhibitor
diabetes mellitus
DPP-4-inhibitor
<i>Ganoderma</i>
in silico
stellasterol
Online Access:https://www.mdpi.com/2218-0532/87/3/21

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