Elucidating the molecular mechanisms underlying the induction of autophagy by antidepressant-like substances in C57BL/6J mouse testis model upon LPS challenge

Elucidating the molecular mechanisms underlying the induction of autophagy by antidepressant-like substances in C57BL/6J mouse testis model upon LPS challenge

Abstract The treatment of depression with pharmaceuticals is associated with many adverse side effects, including male fertility problems. The precise mechanisms by which these agents affect testicular cells remain largely unknown, but they are believed to induce cellular stress, which is sensed by...

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Bibliographic Details
Main Authors: Przemysław Sołek, Ewelina Czechowska, Magdalena Sowa-Kućma, Katarzyna Stachowicz, Piotr Kaczka, Anna Tabęcka-Łonczyńska
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Cell Communication and Signaling
Subjects:
Antidepressant-like substances
Autophagy
Depression
Endoplasmic reticulum
Golgi apparatus
Testis
Online Access:https://doi.org/10.1186/s12964-023-01270-6

Internet

https://doi.org/10.1186/s12964-023-01270-6

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