Applications and Potentials of a Silk Fibroin Nanoparticle Delivery System in Animal Husbandry
Silk fibroin (SF), a unique natural polymeric fibrous protein extracted from <i>Bombyx mori</i> cocoons, accounts for approximately 75% of the total mass of silk. It has great application prospects due to its outstanding biocompatibility, biodegradability, low immunogenicity, and mechani...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-02-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/14/4/655 |
| _version_ | 1797299102376001536 |
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| author | Yiyao Guo Mian Muhammad Awais Shigang Fei Junming Xia Jingchen Sun Min Feng |
| author_facet | Yiyao Guo Mian Muhammad Awais Shigang Fei Junming Xia Jingchen Sun Min Feng |
| author_sort | Yiyao Guo |
| collection | DOAJ |
| description | Silk fibroin (SF), a unique natural polymeric fibrous protein extracted from <i>Bombyx mori</i> cocoons, accounts for approximately 75% of the total mass of silk. It has great application prospects due to its outstanding biocompatibility, biodegradability, low immunogenicity, and mechanical stability. Additionally, it is non-toxic and environmentally friendly. Nanoparticle delivery systems constructed with SF can improve the bioavailability of the carriers, increase the loading rates, control the release behavior of the deliverables, and enhance their action efficiencies. Animal husbandry is an integral part of agriculture and plays a vital role in the development of the rural economy. However, the pillar industry experiences a lot of difficulties, like drug abuse while treating major animal diseases, and serious environmental pollution, restricting sustainable development. Interestingly, the limited use cases of silk fibroin nanoparticle (SF NP) delivery systems in animal husbandry, such as veterinary vaccines and feed additives, have shown great promise. This paper first reviews the SF NP delivery system with regard to its advantages, disadvantages, and applications. Moreover, we describe the application status and developmental prospects of SF NP delivery systems to provide theoretical references for further development in livestock production and promote the high-quality and healthy development of animal husbandry. |
| first_indexed | 2024-03-07T22:45:43Z |
| format | Article |
| id | doaj.art-8b21785b41a94cdbb426f872320e5bbe |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-07T22:45:43Z |
| publishDate | 2024-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-8b21785b41a94cdbb426f872320e5bbe2024-02-23T15:04:57ZengMDPI AGAnimals2076-26152024-02-0114465510.3390/ani14040655Applications and Potentials of a Silk Fibroin Nanoparticle Delivery System in Animal HusbandryYiyao Guo0Mian Muhammad Awais1Shigang Fei2Junming Xia3Jingchen Sun4Min Feng5Guangdong Provincial Key Laboratory of Agro-Animal Genomics and Molecular Breeding, College of Animal Science, South China Agricultural University, Guangzhou 510642, ChinaGuangdong Provincial Key Laboratory of Agro-Animal Genomics and Molecular Breeding, College of Animal Science, South China Agricultural University, Guangzhou 510642, ChinaGuangdong Provincial Key Laboratory of Agro-Animal Genomics and Molecular Breeding, College of Animal Science, South China Agricultural University, Guangzhou 510642, ChinaGuangdong Provincial Key Laboratory of Agro-Animal Genomics and Molecular Breeding, College of Animal Science, South China Agricultural University, Guangzhou 510642, ChinaGuangdong Provincial Key Laboratory of Agro-Animal Genomics and Molecular Breeding, College of Animal Science, South China Agricultural University, Guangzhou 510642, ChinaGuangdong Provincial Key Laboratory of Agro-Animal Genomics and Molecular Breeding, College of Animal Science, South China Agricultural University, Guangzhou 510642, ChinaSilk fibroin (SF), a unique natural polymeric fibrous protein extracted from <i>Bombyx mori</i> cocoons, accounts for approximately 75% of the total mass of silk. It has great application prospects due to its outstanding biocompatibility, biodegradability, low immunogenicity, and mechanical stability. Additionally, it is non-toxic and environmentally friendly. Nanoparticle delivery systems constructed with SF can improve the bioavailability of the carriers, increase the loading rates, control the release behavior of the deliverables, and enhance their action efficiencies. Animal husbandry is an integral part of agriculture and plays a vital role in the development of the rural economy. However, the pillar industry experiences a lot of difficulties, like drug abuse while treating major animal diseases, and serious environmental pollution, restricting sustainable development. Interestingly, the limited use cases of silk fibroin nanoparticle (SF NP) delivery systems in animal husbandry, such as veterinary vaccines and feed additives, have shown great promise. This paper first reviews the SF NP delivery system with regard to its advantages, disadvantages, and applications. Moreover, we describe the application status and developmental prospects of SF NP delivery systems to provide theoretical references for further development in livestock production and promote the high-quality and healthy development of animal husbandry.https://www.mdpi.com/2076-2615/14/4/655silk fibroinnanoparticlesdrug deliveryanimal husbandry |
| spellingShingle | Yiyao Guo Mian Muhammad Awais Shigang Fei Junming Xia Jingchen Sun Min Feng Applications and Potentials of a Silk Fibroin Nanoparticle Delivery System in Animal Husbandry Animals silk fibroin nanoparticles drug delivery animal husbandry |
| title | Applications and Potentials of a Silk Fibroin Nanoparticle Delivery System in Animal Husbandry |
| title_full | Applications and Potentials of a Silk Fibroin Nanoparticle Delivery System in Animal Husbandry |
| title_fullStr | Applications and Potentials of a Silk Fibroin Nanoparticle Delivery System in Animal Husbandry |
| title_full_unstemmed | Applications and Potentials of a Silk Fibroin Nanoparticle Delivery System in Animal Husbandry |
| title_short | Applications and Potentials of a Silk Fibroin Nanoparticle Delivery System in Animal Husbandry |
| title_sort | applications and potentials of a silk fibroin nanoparticle delivery system in animal husbandry |
| topic | silk fibroin nanoparticles drug delivery animal husbandry |
| url | https://www.mdpi.com/2076-2615/14/4/655 |
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