Microfluidics-integrated spaceflight hardware for measuring muscle strength of Caenorhabditis elegans on the International Space Station
Abstract Caenorhabditis elegans is a low-cost genetic model that has been flown to the International Space Station to investigate the influence of microgravity on changes in the expression of genes involved in muscle maintenance. These studies showed that genes that encode muscle attachment complexe...
Main Authors: | Purushottam Soni, Taslim Anupom, Leila Lesanpezeshki, Mizanur Rahman, Jennifer E. Hewitt, Matthew Vellone, Louis Stodieck, Jerzy Blawzdziewicz, Nathaniel J. Szewczyk, Siva A. Vanapalli |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-11-01
|
Series: | npj Microgravity |
Online Access: | https://doi.org/10.1038/s41526-022-00241-4 |
Similar Items
-
Spaceflight Induces Strength Decline in <i>Caenorhabditis elegans</i>
by: Purushottam Soni, et al.
Published: (2023-10-01) -
A Compact Imaging Platform for Conducting <i>C. elegans</i> Phenotypic Assays on Earth and in Spaceflight
by: Taslim Anupom, et al.
Published: (2023-01-01) -
Spaceflight affects neuronal morphology and alters transcellular degradation of neuronal debris in adult Caenorhabditis elegans
by: Ricardo Laranjeiro, et al.
Published: (2021-02-01) -
The effectiveness of RNAi in Caenorhabditis elegans is maintained during spaceflight.
by: Timothy Etheridge, et al.
Published: (2011-01-01) -
Muscle strength deficiency and mitochondrial dysfunction in a muscular dystrophy model of Caenorhabditis elegans and its functional response to drugs
by: Jennifer E. Hewitt, et al.
Published: (2018-12-01)