Chronic Vitamin E Deficiency Dysregulates Purine, Phospholipid, and Amino Acid Metabolism in Aging Zebrafish Skeletal Muscle

Chronic Vitamin E Deficiency Dysregulates Purine, Phospholipid, and Amino Acid Metabolism in Aging Zebrafish Skeletal Muscle

Muscle wasting occurs with aging and may be a result of oxidative stress damage and potentially inadequate protection by lipophilic antioxidants, such as vitamin E. Previous studies have shown muscular abnormalities and behavioral defects in vitamin E-deficient adult zebrafish. To test the hypothesi...

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Bibliographic Details
Main Authors: Trent D. Henderson, Jaewoo Choi, Scott W. Leonard, Brian Head, Robyn L. Tanguay, Carrie L. Barton, Maret G. Traber
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Antioxidants
Subjects:
α-tocopherol
sarcopenia
lipid peroxidation
metabolomics
<i>Danio rerio</i>
Online Access:https://www.mdpi.com/2076-3921/12/6/1160

Internet

https://www.mdpi.com/2076-3921/12/6/1160

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