Fabrication and In Vitro/In Vivo Appraisal of Metronidazole Intra-Gastric Buoyant Sustained-Release Tablets in Healthy Volunteers

Fabrication and In Vitro/In Vivo Appraisal of Metronidazole Intra-Gastric Buoyant Sustained-Release Tablets in Healthy Volunteers

<i>Helicobacter pylori</i> is thought to be the most common cause of peptic and duodenal ulcers. Eradication of this organism is now considered one of the lines of treatment of gastric and duodenal ulcers. This can be achieved via local delivery of antibacterial agents in high concentrat...

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Bibliographic Details
Main Authors: Mohammed H. Elkomy, Heba A. Abou-Taleb, Hussein M. Eid, Heba A. Yassin
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Pharmaceutics
Subjects:
floating tablets
drug delivery system
sustained-release system
HPLC assay of metronidazole
in vitro and in vivo evaluation of metronidazole
Online Access:https://www.mdpi.com/1999-4923/14/4/863

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