Examining the effect of evaluation sample size on the sensitivity and specificity of COVID-19 diagnostic tests in practice: a simulation study

Examining the effect of evaluation sample size on the sensitivity and specificity of COVID-19 diagnostic tests in practice: a simulation study

Abstract Background In response to the global COVID-19 pandemic, many in vitro diagnostic (IVD) tests for SARS-CoV-2 have been developed. Given the urgent clinical demand, researchers must balance the desire for precise estimates of sensitivity and specificity against the need for rapid implementati...

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Bibliographic Details
Main Authors: Camilla Sammut-Powell, Charles Reynard, Joy Allen, John McDermott, Julian Braybrook, Rosa Parisi, Daniel Lasserson, Richard Body, on behalf of the CONDOR steering committee
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Diagnostic and Prognostic Research
Subjects:
COVID-19
Diagnostic accuracy
Research methodology
Statistical study design
Sample size
Online Access:https://doi.org/10.1186/s41512-021-00116-4

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