Coronary artery perforation after bioresorbable scaffold implantation treated with a new generation covered stent—OCT insights

Abstract Background Coronary artery perforation is a rare but potentially lethal complication of percutaneous coronary intervention (PCI) with an associated mortality of 7–17%. We report the case of coronary artery perforation complicating Absorb bioresorbable vascular scaffold (BVS) implantation an...

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Main Authors: D. Chen, R. Gadeley, A. Wang, N. Jepson
Format: Article
Language:English
Published: BMC 2022-02-01
Series:BMC Cardiovascular Disorders
Subjects:
Online Access:https://doi.org/10.1186/s12872-022-02501-3
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author D. Chen
R. Gadeley
A. Wang
N. Jepson
author_facet D. Chen
R. Gadeley
A. Wang
N. Jepson
author_sort D. Chen
collection DOAJ
description Abstract Background Coronary artery perforation is a rare but potentially lethal complication of percutaneous coronary intervention (PCI) with an associated mortality of 7–17%. We report the case of coronary artery perforation complicating Absorb bioresorbable vascular scaffold (BVS) implantation and the associated technical challenges with managing this life-threatening complication. Case report A 46-year-old male was referred to our institution and underwent PCI with an Absorb bioabsorbable vascular scaffold (BVS) to a proximal LAD long segment bifurcation lesion. Following pre-dilation and deployment of the 3.5 × 28 mm Absorb BVS, high pressure post-dilation of the distal scaffold was complicated by a large, Ellis type III coronary perforation with no flow to the distal LAD beyond the rupture, and associated with a large pericardial effusion confirmed on bedside transthoracic echocardiogram (TTE). The insult was temporised with prolonged balloon inflation within the Absorb BVS immediately proximal to the site of perforation, permitting urgent insertion of a pericardial drain. After deflation of the balloon, a 3.0 × 21 mm BeGraft covered stent was deployed across the perforation, restoring normal LAD flow and abolishing the perforation. Cardio-pulmonary resuscitation was not required and the patient remained conscious throughout the procedure. TTE demonstrated normal left ventricular function and the patient was discharged 3 days later. Repeat angiography at 3 months showed patent stents with TIMI III flow, and optical coherence tomography (OCT) showed good expansion and apposition of the proximal Absorb BVS and BeGraft. The patient has remained well 4 years after PCI with no major cardiovascular events. Conclusion The utility of bioresorbable scaffold technology remains controversial although meticulous implantation techniques are associated with improved clinical outcomes. Adoption of the Pre-dilatation, Sizing and Post-dilatation (‘PSP’) method of BVS implantation with routine aggressive vessel preparation and scaffold optimization however may contribute to a higher risk of vessel perforation. The case emphasises the importance of accurate sizing of the vessel with intracoronary imaging and demonstrates the value of newer generation covered stents with single-layer design and slimmer crossing profile producing improved deliverability and procedural success.
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spelling doaj.art-8b2c2bfdb591412cbe973512f44837652022-12-21T21:40:59ZengBMCBMC Cardiovascular Disorders1471-22612022-02-012211710.1186/s12872-022-02501-3Coronary artery perforation after bioresorbable scaffold implantation treated with a new generation covered stent—OCT insightsD. Chen0R. Gadeley1A. Wang2N. Jepson3Prince of Wales HospitalPrince of Wales HospitalUniversity of New South WalesPrince of Wales HospitalAbstract Background Coronary artery perforation is a rare but potentially lethal complication of percutaneous coronary intervention (PCI) with an associated mortality of 7–17%. We report the case of coronary artery perforation complicating Absorb bioresorbable vascular scaffold (BVS) implantation and the associated technical challenges with managing this life-threatening complication. Case report A 46-year-old male was referred to our institution and underwent PCI with an Absorb bioabsorbable vascular scaffold (BVS) to a proximal LAD long segment bifurcation lesion. Following pre-dilation and deployment of the 3.5 × 28 mm Absorb BVS, high pressure post-dilation of the distal scaffold was complicated by a large, Ellis type III coronary perforation with no flow to the distal LAD beyond the rupture, and associated with a large pericardial effusion confirmed on bedside transthoracic echocardiogram (TTE). The insult was temporised with prolonged balloon inflation within the Absorb BVS immediately proximal to the site of perforation, permitting urgent insertion of a pericardial drain. After deflation of the balloon, a 3.0 × 21 mm BeGraft covered stent was deployed across the perforation, restoring normal LAD flow and abolishing the perforation. Cardio-pulmonary resuscitation was not required and the patient remained conscious throughout the procedure. TTE demonstrated normal left ventricular function and the patient was discharged 3 days later. Repeat angiography at 3 months showed patent stents with TIMI III flow, and optical coherence tomography (OCT) showed good expansion and apposition of the proximal Absorb BVS and BeGraft. The patient has remained well 4 years after PCI with no major cardiovascular events. Conclusion The utility of bioresorbable scaffold technology remains controversial although meticulous implantation techniques are associated with improved clinical outcomes. Adoption of the Pre-dilatation, Sizing and Post-dilatation (‘PSP’) method of BVS implantation with routine aggressive vessel preparation and scaffold optimization however may contribute to a higher risk of vessel perforation. The case emphasises the importance of accurate sizing of the vessel with intracoronary imaging and demonstrates the value of newer generation covered stents with single-layer design and slimmer crossing profile producing improved deliverability and procedural success.https://doi.org/10.1186/s12872-022-02501-3CoronaryArteryPerforationBioresorbableStentOptical
spellingShingle D. Chen
R. Gadeley
A. Wang
N. Jepson
Coronary artery perforation after bioresorbable scaffold implantation treated with a new generation covered stent—OCT insights
BMC Cardiovascular Disorders
Coronary
Artery
Perforation
Bioresorbable
Stent
Optical
title Coronary artery perforation after bioresorbable scaffold implantation treated with a new generation covered stent—OCT insights
title_full Coronary artery perforation after bioresorbable scaffold implantation treated with a new generation covered stent—OCT insights
title_fullStr Coronary artery perforation after bioresorbable scaffold implantation treated with a new generation covered stent—OCT insights
title_full_unstemmed Coronary artery perforation after bioresorbable scaffold implantation treated with a new generation covered stent—OCT insights
title_short Coronary artery perforation after bioresorbable scaffold implantation treated with a new generation covered stent—OCT insights
title_sort coronary artery perforation after bioresorbable scaffold implantation treated with a new generation covered stent oct insights
topic Coronary
Artery
Perforation
Bioresorbable
Stent
Optical
url https://doi.org/10.1186/s12872-022-02501-3
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AT rgadeley coronaryarteryperforationafterbioresorbablescaffoldimplantationtreatedwithanewgenerationcoveredstentoctinsights
AT awang coronaryarteryperforationafterbioresorbablescaffoldimplantationtreatedwithanewgenerationcoveredstentoctinsights
AT njepson coronaryarteryperforationafterbioresorbablescaffoldimplantationtreatedwithanewgenerationcoveredstentoctinsights