The effectiveness of mindfulness-based cognitive therapy in depression and serum cortisol levels in women with breast cancer and depressed women
Introduction: This study aims to investigate the effectiveness of mindfulness-based cognitive therapy in depression and serum cortisol levels in women with breast cancer and depressed women. Materials and Methods: In this clinical trial, 30 women with breast cancer who referred to Omid Hospital, M...
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2022-11-01
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| Series: | Journal of Fundamentals of Mental Health |
| Subjects: | |
| Online Access: | https://jfmh.mums.ac.ir/article_21513_9ad041e729531c97f49f600408ff0556.pdf |
| _version_ | 1811291459830153216 |
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| author | Zahra Olyaee Masoud Mohammadi Kazem Anvari Seyed Ebrahim Hosseini |
| author_facet | Zahra Olyaee Masoud Mohammadi Kazem Anvari Seyed Ebrahim Hosseini |
| author_sort | Zahra Olyaee |
| collection | DOAJ |
| description | Introduction: This study aims to investigate the effectiveness of mindfulness-based cognitive therapy in depression and serum cortisol levels in women with breast cancer and depressed women.
Materials and Methods: In this clinical trial, 30 women with breast cancer who referred to Omid Hospital, Mashhad-Iran and 30 women with depression who referred to counseling clinics of Mashhad in 2020-2021 were selected by the convenience sampling method and were randomly assigned to four equal groups (2 experimental groups and 2 control groups). The experimental groups received mindfulness-based cognitive therapy during eight 90-120 minute sessions per week, while the control group did not receive any intervention. Research instruments included the Depression Inventory (BDI-II) and the blood samples to evaluate the cortisol levels. Data were analyzed through descriptive statistics, and the covariance analysis.
Results: The results of depressed people demonstrated that mindfulness-based cognitive therapy is effective to reduce depression and serum cortisol levels within the normal laboratory range (P< 0.001). Further, the findings of breast cancer women indicated that mindfulness-based cognitive therapy reduced depression and increased serum cortisol from low to moderate levels within the normal laboratory range (P< 0.001).
Conclusion: Mindfulness-based cognitive therapy can be effective in neurobiological mechanisms in addition to improving psychological symptoms in depressed individuals and cancer patients. |
| first_indexed | 2024-04-13T04:29:45Z |
| format | Article |
| id | doaj.art-8b2cab55880a457db4f022ff0cd1e95a |
| institution | Directory Open Access Journal |
| issn | 1028-6918 1684-4300 |
| language | English |
| last_indexed | 2024-04-13T04:29:45Z |
| publishDate | 2022-11-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Journal of Fundamentals of Mental Health |
| spelling | doaj.art-8b2cab55880a457db4f022ff0cd1e95a2022-12-22T03:02:22ZengMashhad University of Medical SciencesJournal of Fundamentals of Mental Health1028-69181684-43002022-11-0124641942610.22038/jfmh.2022.2151321513The effectiveness of mindfulness-based cognitive therapy in depression and serum cortisol levels in women with breast cancer and depressed womenZahra Olyaee0Masoud Mohammadi1Kazem Anvari2Seyed Ebrahim Hosseini3Ph.D. student, Department of Clinical Psychology, Shiraz Branch, Islamic Azad University, Shiraz, Iran.Assistant professor, Department of Clinical of Psychology, Shiraz Branch, Islamic Azad University, Shiraz, Iran.Professor, Department of Radiology, Medical School, Mashhad University of Medical Sciences, Mashhad, Iran.Associate Professor Department of physiology, Shiraz Branch, Faculty of Science, Zand Institute of Higher Education, Shiraz, Iran.Introduction: This study aims to investigate the effectiveness of mindfulness-based cognitive therapy in depression and serum cortisol levels in women with breast cancer and depressed women. Materials and Methods: In this clinical trial, 30 women with breast cancer who referred to Omid Hospital, Mashhad-Iran and 30 women with depression who referred to counseling clinics of Mashhad in 2020-2021 were selected by the convenience sampling method and were randomly assigned to four equal groups (2 experimental groups and 2 control groups). The experimental groups received mindfulness-based cognitive therapy during eight 90-120 minute sessions per week, while the control group did not receive any intervention. Research instruments included the Depression Inventory (BDI-II) and the blood samples to evaluate the cortisol levels. Data were analyzed through descriptive statistics, and the covariance analysis. Results: The results of depressed people demonstrated that mindfulness-based cognitive therapy is effective to reduce depression and serum cortisol levels within the normal laboratory range (P< 0.001). Further, the findings of breast cancer women indicated that mindfulness-based cognitive therapy reduced depression and increased serum cortisol from low to moderate levels within the normal laboratory range (P< 0.001). Conclusion: Mindfulness-based cognitive therapy can be effective in neurobiological mechanisms in addition to improving psychological symptoms in depressed individuals and cancer patients.https://jfmh.mums.ac.ir/article_21513_9ad041e729531c97f49f600408ff0556.pdfcancercortisoldepressionmindfulness-based cognitive therapy |
| spellingShingle | Zahra Olyaee Masoud Mohammadi Kazem Anvari Seyed Ebrahim Hosseini The effectiveness of mindfulness-based cognitive therapy in depression and serum cortisol levels in women with breast cancer and depressed women Journal of Fundamentals of Mental Health cancer cortisol depression mindfulness-based cognitive therapy |
| title | The effectiveness of mindfulness-based cognitive therapy in depression and serum cortisol levels in women with breast cancer and depressed women |
| title_full | The effectiveness of mindfulness-based cognitive therapy in depression and serum cortisol levels in women with breast cancer and depressed women |
| title_fullStr | The effectiveness of mindfulness-based cognitive therapy in depression and serum cortisol levels in women with breast cancer and depressed women |
| title_full_unstemmed | The effectiveness of mindfulness-based cognitive therapy in depression and serum cortisol levels in women with breast cancer and depressed women |
| title_short | The effectiveness of mindfulness-based cognitive therapy in depression and serum cortisol levels in women with breast cancer and depressed women |
| title_sort | effectiveness of mindfulness based cognitive therapy in depression and serum cortisol levels in women with breast cancer and depressed women |
| topic | cancer cortisol depression mindfulness-based cognitive therapy |
| url | https://jfmh.mums.ac.ir/article_21513_9ad041e729531c97f49f600408ff0556.pdf |
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