Early Activation of MAPK p44/42 Is Partially Involved in DON-Induced Disruption of the Intestinal Barrier Function and Tight Junction Network

Early Activation of MAPK p44/42 Is Partially Involved in DON-Induced Disruption of the Intestinal Barrier Function and Tight Junction Network

Deoxynivalenol (DON), produced by the plant pathogens Fusarium graminearum and Fusarium culmorum, is one of the most common mycotoxins, contaminating cereal and cereal-derived products. Although worldwide contamination of food and feed poses health threats to humans and animals, pigs are particularl...

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Bibliographic Details
Main Authors: Alexandra Springler, Sabine Hessenberger, Gerd Schatzmayr, Elisabeth Mayer
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:Toxins
Subjects:
transepithelial electrical resistance
mycotoxin
IPEC-J2
tight junctions
deoxynivalenol
de-epoxy deoxynivalenol
Online Access:http://www.mdpi.com/2072-6651/8/9/264

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