Coupling of H3K27me3 recognition with transcriptional repression through the BAH-PHD-CPL2 complex in Arabidopsis
Histone 3 Lys 27 trimethylation (H3K27me3) mediates epigenetic silencing of gene expression. Here, Zhang et al. show that in Arabidopsis, the BAH-domain H3K27me3-reader protein AIPP3 forms a complex with PHD proteins and CPL2, a plant-specific Pol II phosphatase, to inhibit Pol II activity by dephos...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2020-12-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-020-20089-0 |
| _version_ | 1818851510172254208 |
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| author | Yi-Zhe Zhang Jianlong Yuan Lingrui Zhang Chunxiang Chen Yuhua Wang Guiping Zhang Li Peng Si-Si Xie Jing Jiang Jian-Kang Zhu Jiamu Du Cheng-Guo Duan |
| author_facet | Yi-Zhe Zhang Jianlong Yuan Lingrui Zhang Chunxiang Chen Yuhua Wang Guiping Zhang Li Peng Si-Si Xie Jing Jiang Jian-Kang Zhu Jiamu Du Cheng-Guo Duan |
| author_sort | Yi-Zhe Zhang |
| collection | DOAJ |
| description | Histone 3 Lys 27 trimethylation (H3K27me3) mediates epigenetic silencing of gene expression. Here, Zhang et al. show that in Arabidopsis, the BAH-domain H3K27me3-reader protein AIPP3 forms a complex with PHD proteins and CPL2, a plant-specific Pol II phosphatase, to inhibit Pol II activity by dephosphorylation. |
| first_indexed | 2024-12-19T07:06:10Z |
| format | Article |
| id | doaj.art-8b32383d6ce641d7b7a43cd4cb33d8c1 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-19T07:06:10Z |
| publishDate | 2020-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-8b32383d6ce641d7b7a43cd4cb33d8c12022-12-21T20:31:17ZengNature PortfolioNature Communications2041-17232020-12-0111111610.1038/s41467-020-20089-0Coupling of H3K27me3 recognition with transcriptional repression through the BAH-PHD-CPL2 complex in ArabidopsisYi-Zhe Zhang0Jianlong Yuan1Lingrui Zhang2Chunxiang Chen3Yuhua Wang4Guiping Zhang5Li Peng6Si-Si Xie7Jing Jiang8Jian-Kang Zhu9Jiamu Du10Cheng-Guo Duan11Shanghai Center for Plant Stress Biology and CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of SciencesShanghai Center for Plant Stress Biology and CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of SciencesDepartment of Horticulture and Landscape Architecture, Purdue UniversityShanghai Center for Plant Stress Biology and CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of SciencesShanghai Center for Plant Stress Biology and CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of SciencesShanghai Center for Plant Stress Biology and CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of SciencesShanghai Center for Plant Stress Biology and CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of SciencesShanghai Center for Plant Stress Biology and CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of SciencesState Key Laboratory of Crop Stress Adaptation and Improvement, School of Life Sciences, Henan UniversityShanghai Center for Plant Stress Biology and CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of SciencesKey Laboratory of Molecular Design for Plant Cell Factory of Guangdong Higher Education Institutes, Institute of Plant and Food Science, School of Life Sciences, Southern University of Science and TechnologyShanghai Center for Plant Stress Biology and CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of SciencesHistone 3 Lys 27 trimethylation (H3K27me3) mediates epigenetic silencing of gene expression. Here, Zhang et al. show that in Arabidopsis, the BAH-domain H3K27me3-reader protein AIPP3 forms a complex with PHD proteins and CPL2, a plant-specific Pol II phosphatase, to inhibit Pol II activity by dephosphorylation.https://doi.org/10.1038/s41467-020-20089-0 |
| spellingShingle | Yi-Zhe Zhang Jianlong Yuan Lingrui Zhang Chunxiang Chen Yuhua Wang Guiping Zhang Li Peng Si-Si Xie Jing Jiang Jian-Kang Zhu Jiamu Du Cheng-Guo Duan Coupling of H3K27me3 recognition with transcriptional repression through the BAH-PHD-CPL2 complex in Arabidopsis Nature Communications |
| title | Coupling of H3K27me3 recognition with transcriptional repression through the BAH-PHD-CPL2 complex in Arabidopsis |
| title_full | Coupling of H3K27me3 recognition with transcriptional repression through the BAH-PHD-CPL2 complex in Arabidopsis |
| title_fullStr | Coupling of H3K27me3 recognition with transcriptional repression through the BAH-PHD-CPL2 complex in Arabidopsis |
| title_full_unstemmed | Coupling of H3K27me3 recognition with transcriptional repression through the BAH-PHD-CPL2 complex in Arabidopsis |
| title_short | Coupling of H3K27me3 recognition with transcriptional repression through the BAH-PHD-CPL2 complex in Arabidopsis |
| title_sort | coupling of h3k27me3 recognition with transcriptional repression through the bah phd cpl2 complex in arabidopsis |
| url | https://doi.org/10.1038/s41467-020-20089-0 |
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