Development of microextraction methods for the determination of sulfamethoxazole in water and biological samples: modelling, optimization and verification by central composite design
This study aimed to preconcentration of sulfamethoxazole (SMX) in water and biological samples. Ultrasound-assisted dispersive liquid-liquid microextraction (UA-DLLME) and ultrasound-assisted dispersive solid-phase microextraction (UA-DSPME) methods paired with spectrophotometry were applied to extr...
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| Format: | Article |
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Frontiers Media S.A.
2023-08-01
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| Series: | Frontiers in Environmental Science |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fenvs.2023.1242730/full |
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| author | Issa Sheibani Amin Ali Naser Neysari Raed H. Althomali Ebraheem Abdu Musad Saleh Sayfiddin Baymakov Sayfiddin Baymakov Ahmed Hussien Radie Alawady Ahmed Hussien Radie Alawady Ahmed Hussien Radie Alawady Ali Hashiem Alsaalamy Montather F. Ramadan Ashima Juyal |
| author_facet | Issa Sheibani Amin Ali Naser Neysari Raed H. Althomali Ebraheem Abdu Musad Saleh Sayfiddin Baymakov Sayfiddin Baymakov Ahmed Hussien Radie Alawady Ahmed Hussien Radie Alawady Ahmed Hussien Radie Alawady Ali Hashiem Alsaalamy Montather F. Ramadan Ashima Juyal |
| author_sort | Issa Sheibani Amin |
| collection | DOAJ |
| description | This study aimed to preconcentration of sulfamethoxazole (SMX) in water and biological samples. Ultrasound-assisted dispersive liquid-liquid microextraction (UA-DLLME) and ultrasound-assisted dispersive solid-phase microextraction (UA-DSPME) methods paired with spectrophotometry were applied to extraction and preconcentration of SMX. ZnFe2O4 nanoparticles were prepared as adsorbent in UA-DSPME method by hydrothermal method. The scanning electron microscopy (SEM) technique showed that the adsorbent had symmetrical, bullet-shaped particles with uniform size. The results of the X-ray diffraction (XRD) showed the successful synthesis of the ZnFe2O4 nanoparticles. Effective parameters in extraction, including ultrasonication time, disperser solvent volume, adsorbent amount, extraction solvent volume, eluent volume, and pH were investigated and optimized. The practical and optimal conditions of the process were determined by the central composite design (CCD). The optimal conditions were 0.024 g of adsorbent, 535 µL of disperser solvent volume, 7.5 min of ultrasonication time, 235 µL of eluent volume, pH of 5, and 185 µL of extraction solvent volume. Linear ranges and detection limits were 20–1,200 μg L−1 and 6 μg L−1 for UA-DSPME and 10–800 μg L−1 and 3 μg L−1 for UA-DLLME. Relative standard deviation (RSD) of less than 4% were obtained for UA-DSPME and UA-DLLME methods. The reusability showed that the ZnFe2O4 adsorbent could extract SMX up to five cycles of adsorption/desorption without significant reduction in its efficiency. Also, interference studies showed that the presence of different cations and anions did not significantly interfere in the extraction of SMX. The outcomes of real-time samples analysis showed that the extraction of SMX for both methods was in the range of 92.44%–99.12%. The results showed the developed methods are simple, sensitive, and suitable for SMX preconcentration in environmental water and biological samples. |
| first_indexed | 2024-03-12T14:04:54Z |
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| id | doaj.art-8b3466ab12044c60b3e0caadf9e1c0c3 |
| institution | Directory Open Access Journal |
| issn | 2296-665X |
| language | English |
| last_indexed | 2024-03-12T14:04:54Z |
| publishDate | 2023-08-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Environmental Science |
| spelling | doaj.art-8b3466ab12044c60b3e0caadf9e1c0c32023-08-21T14:32:07ZengFrontiers Media S.A.Frontiers in Environmental Science2296-665X2023-08-011110.3389/fenvs.2023.12427301242730Development of microextraction methods for the determination of sulfamethoxazole in water and biological samples: modelling, optimization and verification by central composite designIssa Sheibani Amin0Ali Naser Neysari1Raed H. Althomali2Ebraheem Abdu Musad Saleh3Sayfiddin Baymakov4Sayfiddin Baymakov5Ahmed Hussien Radie Alawady6Ahmed Hussien Radie Alawady7Ahmed Hussien Radie Alawady8Ali Hashiem Alsaalamy9Montather F. Ramadan10Ashima Juyal11Department of Urban Planning, Faculty of Social Sciences, Payame Noor University, Tehran, IranCivil Engineering-Water Resources Engineering and Management, Sharif University of Technology, Tehran, IranDepartment of Chemistry, College of Arts and Science, Prince Sattam Bin Abdulaziz University, Wadi Al-Dawasir, Saudi ArabiaDepartment of Chemistry, College of Arts and Science, Prince Sattam Bin Abdulaziz University, Wadi Al-Dawasir, Saudi ArabiaDepartment of General Surgery and Military-Field Surgery, Tashkent State Dental Institute, Tashkent, UzbekistanDepartment of Scientific Affairs, Samarkand State Dental Institute, Samarkand, UzbekistanCollege of Technical Engineering, The Islamic University of Najaf, Najaf, IraqCollege of Technical Engineering, The Islamic University of Al Diwaniyah, Al Diwaniyah, IraqCollege of Technical Engineering, The Islamic University of Babylon, Babylon, IraqCollege of Technical Engineering, Imam Ja’afar Al‐Sadiq University, Al-Muthanna, Iraq0College of Dentistry, Al-Ayen University, Thi-Qar, Iraq1Department of Electronics and Communication Engineering, Uttaranchal Institute of Technology, Uttaranchal University, Dehradun, IndiaThis study aimed to preconcentration of sulfamethoxazole (SMX) in water and biological samples. Ultrasound-assisted dispersive liquid-liquid microextraction (UA-DLLME) and ultrasound-assisted dispersive solid-phase microextraction (UA-DSPME) methods paired with spectrophotometry were applied to extraction and preconcentration of SMX. ZnFe2O4 nanoparticles were prepared as adsorbent in UA-DSPME method by hydrothermal method. The scanning electron microscopy (SEM) technique showed that the adsorbent had symmetrical, bullet-shaped particles with uniform size. The results of the X-ray diffraction (XRD) showed the successful synthesis of the ZnFe2O4 nanoparticles. Effective parameters in extraction, including ultrasonication time, disperser solvent volume, adsorbent amount, extraction solvent volume, eluent volume, and pH were investigated and optimized. The practical and optimal conditions of the process were determined by the central composite design (CCD). The optimal conditions were 0.024 g of adsorbent, 535 µL of disperser solvent volume, 7.5 min of ultrasonication time, 235 µL of eluent volume, pH of 5, and 185 µL of extraction solvent volume. Linear ranges and detection limits were 20–1,200 μg L−1 and 6 μg L−1 for UA-DSPME and 10–800 μg L−1 and 3 μg L−1 for UA-DLLME. Relative standard deviation (RSD) of less than 4% were obtained for UA-DSPME and UA-DLLME methods. The reusability showed that the ZnFe2O4 adsorbent could extract SMX up to five cycles of adsorption/desorption without significant reduction in its efficiency. Also, interference studies showed that the presence of different cations and anions did not significantly interfere in the extraction of SMX. The outcomes of real-time samples analysis showed that the extraction of SMX for both methods was in the range of 92.44%–99.12%. The results showed the developed methods are simple, sensitive, and suitable for SMX preconcentration in environmental water and biological samples.https://www.frontiersin.org/articles/10.3389/fenvs.2023.1242730/fulldispersive liquid-liquid microextractiondispersive solid-phase microextractionresponse surface methodologysulfamethoxazoleultrasonic-assisted extraction (UAE) |
| spellingShingle | Issa Sheibani Amin Ali Naser Neysari Raed H. Althomali Ebraheem Abdu Musad Saleh Sayfiddin Baymakov Sayfiddin Baymakov Ahmed Hussien Radie Alawady Ahmed Hussien Radie Alawady Ahmed Hussien Radie Alawady Ali Hashiem Alsaalamy Montather F. Ramadan Ashima Juyal Development of microextraction methods for the determination of sulfamethoxazole in water and biological samples: modelling, optimization and verification by central composite design Frontiers in Environmental Science dispersive liquid-liquid microextraction dispersive solid-phase microextraction response surface methodology sulfamethoxazole ultrasonic-assisted extraction (UAE) |
| title | Development of microextraction methods for the determination of sulfamethoxazole in water and biological samples: modelling, optimization and verification by central composite design |
| title_full | Development of microextraction methods for the determination of sulfamethoxazole in water and biological samples: modelling, optimization and verification by central composite design |
| title_fullStr | Development of microextraction methods for the determination of sulfamethoxazole in water and biological samples: modelling, optimization and verification by central composite design |
| title_full_unstemmed | Development of microextraction methods for the determination of sulfamethoxazole in water and biological samples: modelling, optimization and verification by central composite design |
| title_short | Development of microextraction methods for the determination of sulfamethoxazole in water and biological samples: modelling, optimization and verification by central composite design |
| title_sort | development of microextraction methods for the determination of sulfamethoxazole in water and biological samples modelling optimization and verification by central composite design |
| topic | dispersive liquid-liquid microextraction dispersive solid-phase microextraction response surface methodology sulfamethoxazole ultrasonic-assisted extraction (UAE) |
| url | https://www.frontiersin.org/articles/10.3389/fenvs.2023.1242730/full |
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