An Inactivated Influenza Virus Vaccine Approach to Targeting the Conserved Hemagglutinin Stalk and M2e Domains

An Inactivated Influenza Virus Vaccine Approach to Targeting the Conserved Hemagglutinin Stalk and M2e Domains

Universal influenza virus vaccine candidates that focus on the conserved hemagglutinin (HA) stalk domain and the extracellular domain of the matrix protein 2 (M2e) have been developed to increase the breadth of protection against multiple strains. In this study, we report a novel inactivated influen...

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Bibliographic Details
Main Authors: Weina Sun, Allen Zheng, Robert Miller, Florian Krammer, Peter Palese
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Vaccines
Subjects:
cross-protection
ADCC
conserved epitopes
universal influenza virus vaccine
enhanced immunogenicity
immunodominance
Online Access:https://www.mdpi.com/2076-393X/7/3/117

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