Enhancing de novo ceramide synthesis induced by bisphenol A exposure aggravates metabolic derangement during obesity
Objective: Exposure to bisphenol A (BPA) has been shown to increase the prevalence of obesity and its related insulin resistance (IR). Ceramide is a sphingolipid known to facilitate the production of proinflammatory cytokines and subsequently exacerbate inflammation and IR during the progression of...
Main Authors: | Gengfu Wang, Xu Hong, Jia Yu, Yuheng Zhang, Yuting Li, Zuo Li, Zhiyuan Zhu, Shaoyun Yuan, Xiaofei Zhang, Sheng Wang, Fuhai Zhu, Yong Wang, Changhao Wu, Puyu Su, Tong Shen |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2023-07-01
|
Series: | Molecular Metabolism |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2212877823000753 |
Similar Items
-
Inhibition of Ceramide Synthesis Reduces α-Synuclein Proteinopathy in a Cellular Model of Parkinson’s Disease
by: Alessandra Mingione, et al.
Published: (2021-06-01) -
Vitamin K2 as a New Modulator of the Ceramide De Novo Synthesis Pathway
by: Adrian Kołakowski, et al.
Published: (2021-06-01) -
A Dansyl-Modified Sphingosine Kinase Inhibitor DPF-543 Enhanced De Novo Ceramide Generation
by: Maftuna Shamshiddinova, et al.
Published: (2021-08-01) -
Ceramides: focus on obesity
by: Yulia A. Dyleva, et al.
Published: (2020-12-01) -
Environmental endocrine disruptor Bisphenol A induces metabolic derailment and obesity via upregulating IL-17A in adipocytes
by: Xu Hong, et al.
Published: (2023-02-01)