Serum levels of organochlorine pesticides and polychlorinated biphenyls among inhabitants of Greater Metropolitan Rio de Janeiro, Brazil
Levels of persistent organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) were determined in the blood serum of people living and working in the urban area of greater Rio de Janeiro city. Blood samples from 33 volunteers (16 males, 17 females, 19-63 years old) were taken in January...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Sprog: | English |
Udgivet: |
Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz
2002-01-01
|
Serier: | Cadernos de Saúde Pública |
Fag: | |
Online adgang: | http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0102-311X2002000200017 |
_version_ | 1828436502612279296 |
---|---|
author | Delgado Isabella Fernandes Barretto Heloisa H.C. Kussumi Teresa A. Alleluia Irene Baptista Baggio Cenira de A. Paumgartten Francisco José Roma |
author_facet | Delgado Isabella Fernandes Barretto Heloisa H.C. Kussumi Teresa A. Alleluia Irene Baptista Baggio Cenira de A. Paumgartten Francisco José Roma |
author_sort | Delgado Isabella Fernandes |
collection | DOAJ |
description | Levels of persistent organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) were determined in the blood serum of people living and working in the urban area of greater Rio de Janeiro city. Blood samples from 33 volunteers (16 males, 17 females, 19-63 years old) were taken in January 1999. OCP residues (op'DDT, pp'DDT, pp'DDD, pp'DDE, Aldrin, Dieldrin, Endrin, Heptachlor, Heptachlor-epoxide, alpha-, beta- and gamma-Hexachlorocyclo-hexane, Hexachlorobenzene) and PCBs (congeners: 28, 52, 101, 138, 153, 180) were extracted with n-hexane and analyzed by gas chromatography with electron capture detection. Except for pp'DDE (detection limit = 1.4µg/L) no other OCP residue was found in the samples. No PCB congener (detection limit = 2.0µg/L) was detected either. pp'DDE was found in 17 out of 33 samples in concentrations that ranged from 1.4 to 8.4 µg/L of serum or, on a fat basis, from 0.200 to 3.452 µg/g of serum lipids. Percentage of positive samples (%) and levels of pp'DDE (range of positive samples) increased from the youngest to the oldest group (<=29 yrs: 10%, 0.278µg/g; 30-39 yrs: 60%, 0.200-0.765µg/g; > or = 40 yrs: 77%, 0.257-3.452µg/g). |
first_indexed | 2024-12-10T19:26:55Z |
format | Article |
id | doaj.art-8b36e7e0429f4aa6b51a05c4c8eb6402 |
institution | Directory Open Access Journal |
issn | 0102-311X 1678-4464 |
language | English |
last_indexed | 2024-12-10T19:26:55Z |
publishDate | 2002-01-01 |
publisher | Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz |
record_format | Article |
series | Cadernos de Saúde Pública |
spelling | doaj.art-8b36e7e0429f4aa6b51a05c4c8eb64022022-12-22T01:36:20ZengEscola Nacional de Saúde Pública, Fundação Oswaldo CruzCadernos de Saúde Pública0102-311X1678-44642002-01-01182519524Serum levels of organochlorine pesticides and polychlorinated biphenyls among inhabitants of Greater Metropolitan Rio de Janeiro, BrazilDelgado Isabella FernandesBarretto Heloisa H.C.Kussumi Teresa A.Alleluia Irene BaptistaBaggio Cenira de A.Paumgartten Francisco José RomaLevels of persistent organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) were determined in the blood serum of people living and working in the urban area of greater Rio de Janeiro city. Blood samples from 33 volunteers (16 males, 17 females, 19-63 years old) were taken in January 1999. OCP residues (op'DDT, pp'DDT, pp'DDD, pp'DDE, Aldrin, Dieldrin, Endrin, Heptachlor, Heptachlor-epoxide, alpha-, beta- and gamma-Hexachlorocyclo-hexane, Hexachlorobenzene) and PCBs (congeners: 28, 52, 101, 138, 153, 180) were extracted with n-hexane and analyzed by gas chromatography with electron capture detection. Except for pp'DDE (detection limit = 1.4µg/L) no other OCP residue was found in the samples. No PCB congener (detection limit = 2.0µg/L) was detected either. pp'DDE was found in 17 out of 33 samples in concentrations that ranged from 1.4 to 8.4 µg/L of serum or, on a fat basis, from 0.200 to 3.452 µg/g of serum lipids. Percentage of positive samples (%) and levels of pp'DDE (range of positive samples) increased from the youngest to the oldest group (<=29 yrs: 10%, 0.278µg/g; 30-39 yrs: 60%, 0.200-0.765µg/g; > or = 40 yrs: 77%, 0.257-3.452µg/g).http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0102-311X2002000200017Organic ChemicalsDDTPolychlorinated BiphenylsEndocrine Disruptors |
spellingShingle | Delgado Isabella Fernandes Barretto Heloisa H.C. Kussumi Teresa A. Alleluia Irene Baptista Baggio Cenira de A. Paumgartten Francisco José Roma Serum levels of organochlorine pesticides and polychlorinated biphenyls among inhabitants of Greater Metropolitan Rio de Janeiro, Brazil Cadernos de Saúde Pública Organic Chemicals DDT Polychlorinated Biphenyls Endocrine Disruptors |
title | Serum levels of organochlorine pesticides and polychlorinated biphenyls among inhabitants of Greater Metropolitan Rio de Janeiro, Brazil |
title_full | Serum levels of organochlorine pesticides and polychlorinated biphenyls among inhabitants of Greater Metropolitan Rio de Janeiro, Brazil |
title_fullStr | Serum levels of organochlorine pesticides and polychlorinated biphenyls among inhabitants of Greater Metropolitan Rio de Janeiro, Brazil |
title_full_unstemmed | Serum levels of organochlorine pesticides and polychlorinated biphenyls among inhabitants of Greater Metropolitan Rio de Janeiro, Brazil |
title_short | Serum levels of organochlorine pesticides and polychlorinated biphenyls among inhabitants of Greater Metropolitan Rio de Janeiro, Brazil |
title_sort | serum levels of organochlorine pesticides and polychlorinated biphenyls among inhabitants of greater metropolitan rio de janeiro brazil |
topic | Organic Chemicals DDT Polychlorinated Biphenyls Endocrine Disruptors |
url | http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0102-311X2002000200017 |
work_keys_str_mv | AT delgadoisabellafernandes serumlevelsoforganochlorinepesticidesandpolychlorinatedbiphenylsamonginhabitantsofgreatermetropolitanriodejaneirobrazil AT barrettoheloisahc serumlevelsoforganochlorinepesticidesandpolychlorinatedbiphenylsamonginhabitantsofgreatermetropolitanriodejaneirobrazil AT kussumiteresaa serumlevelsoforganochlorinepesticidesandpolychlorinatedbiphenylsamonginhabitantsofgreatermetropolitanriodejaneirobrazil AT alleluiairenebaptista serumlevelsoforganochlorinepesticidesandpolychlorinatedbiphenylsamonginhabitantsofgreatermetropolitanriodejaneirobrazil AT baggioceniradea serumlevelsoforganochlorinepesticidesandpolychlorinatedbiphenylsamonginhabitantsofgreatermetropolitanriodejaneirobrazil AT paumgarttenfranciscojoseroma serumlevelsoforganochlorinepesticidesandpolychlorinatedbiphenylsamonginhabitantsofgreatermetropolitanriodejaneirobrazil |