Diagnostic accuracy of haemophilia early arthropathy detection with ultrasound (HEAD-US): a comparative magnetic resonance imaging (MRI) study
Repeated haemarthroses affect approximately 90% of patients with severe haemophilia and lead to progressive arthropathy, which is the main cause of morbidity in these patients. Diagnostic imaging can detect even subclinical arthropathy changes and may impact prophylactic treatment. Magnetic resonanc...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sciendo
2019-06-01
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| Series: | Radiology and Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.2478/raon-2019-0027 |
| _version_ | 1818689067310645248 |
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| author | Plut Domen Kotnik Barbara Faganel Zupan Irena Preloznik Kljucevsek Damjana Vidmar Gaj Snoj Ziga Martinoli Carlo Salapura Vladka |
| author_facet | Plut Domen Kotnik Barbara Faganel Zupan Irena Preloznik Kljucevsek Damjana Vidmar Gaj Snoj Ziga Martinoli Carlo Salapura Vladka |
| author_sort | Plut Domen |
| collection | DOAJ |
| description | Repeated haemarthroses affect approximately 90% of patients with severe haemophilia and lead to progressive arthropathy, which is the main cause of morbidity in these patients. Diagnostic imaging can detect even subclinical arthropathy changes and may impact prophylactic treatment. Magnetic resonance imagining (MRI) is generally the gold standard tool for precise evaluation of joints, but it is not easily feasible in regular follow-up of patients with haemophilia. The development of the standardized ultrasound (US) protocol for detection of early changes in haemophilic arthropathy (HEAD-US) opened new perspectives in the use of US in management of these patients. The HEAD-US protocol enables quick evaluation of the six mostly affected joints in a single study. The aim of this prospective study was to determine the diagnostic accuracy of the HEAD-US protocol for the detection and quantification of haemophilic arthropathy in comparison to the MRI. |
| first_indexed | 2024-12-17T12:04:13Z |
| format | Article |
| id | doaj.art-8b3744ccf2bd4b7f92716551b604146f |
| institution | Directory Open Access Journal |
| issn | 1581-3207 |
| language | English |
| last_indexed | 2024-12-17T12:04:13Z |
| publishDate | 2019-06-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Radiology and Oncology |
| spelling | doaj.art-8b3744ccf2bd4b7f92716551b604146f2022-12-21T21:49:42ZengSciendoRadiology and Oncology1581-32072019-06-0153217818610.2478/raon-2019-0027raon-2019-0027Diagnostic accuracy of haemophilia early arthropathy detection with ultrasound (HEAD-US): a comparative magnetic resonance imaging (MRI) studyPlut Domen0Kotnik Barbara Faganel1Zupan Irena Preloznik2Kljucevsek Damjana3Vidmar Gaj4Snoj Ziga5Martinoli Carlo6Salapura Vladka7Clinical Radiology Institute, University Medical Centre Ljubljana, Ljubljana, SloveniaFaculty of Medicine, University of Ljubljana, Ljubljana, SloveniaFaculty of Medicine, University of Ljubljana, Ljubljana, SloveniaFaculty of Medicine, University of Ljubljana, Ljubljana, SloveniaFaculty of Medicine, University of Ljubljana, Ljubljana, SloveniaClinical Radiology Institute, University Medical Centre Ljubljana, Ljubljana, SloveniaSchool of Medicine and Pharmacy, University of Genoa, Genoa, ItalyClinical Radiology Institute, University Medical Centre Ljubljana, Ljubljana, SloveniaRepeated haemarthroses affect approximately 90% of patients with severe haemophilia and lead to progressive arthropathy, which is the main cause of morbidity in these patients. Diagnostic imaging can detect even subclinical arthropathy changes and may impact prophylactic treatment. Magnetic resonance imagining (MRI) is generally the gold standard tool for precise evaluation of joints, but it is not easily feasible in regular follow-up of patients with haemophilia. The development of the standardized ultrasound (US) protocol for detection of early changes in haemophilic arthropathy (HEAD-US) opened new perspectives in the use of US in management of these patients. The HEAD-US protocol enables quick evaluation of the six mostly affected joints in a single study. The aim of this prospective study was to determine the diagnostic accuracy of the HEAD-US protocol for the detection and quantification of haemophilic arthropathy in comparison to the MRI.https://doi.org/10.2478/raon-2019-0027haemophiliahaemophilic arthropathyhead-usultrasoundmagnetic resonance imaging |
| spellingShingle | Plut Domen Kotnik Barbara Faganel Zupan Irena Preloznik Kljucevsek Damjana Vidmar Gaj Snoj Ziga Martinoli Carlo Salapura Vladka Diagnostic accuracy of haemophilia early arthropathy detection with ultrasound (HEAD-US): a comparative magnetic resonance imaging (MRI) study Radiology and Oncology haemophilia haemophilic arthropathy head-us ultrasound magnetic resonance imaging |
| title | Diagnostic accuracy of haemophilia early arthropathy detection with ultrasound (HEAD-US): a comparative magnetic resonance imaging (MRI) study |
| title_full | Diagnostic accuracy of haemophilia early arthropathy detection with ultrasound (HEAD-US): a comparative magnetic resonance imaging (MRI) study |
| title_fullStr | Diagnostic accuracy of haemophilia early arthropathy detection with ultrasound (HEAD-US): a comparative magnetic resonance imaging (MRI) study |
| title_full_unstemmed | Diagnostic accuracy of haemophilia early arthropathy detection with ultrasound (HEAD-US): a comparative magnetic resonance imaging (MRI) study |
| title_short | Diagnostic accuracy of haemophilia early arthropathy detection with ultrasound (HEAD-US): a comparative magnetic resonance imaging (MRI) study |
| title_sort | diagnostic accuracy of haemophilia early arthropathy detection with ultrasound head us a comparative magnetic resonance imaging mri study |
| topic | haemophilia haemophilic arthropathy head-us ultrasound magnetic resonance imaging |
| url | https://doi.org/10.2478/raon-2019-0027 |
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