Multiple local recurrences of primary sternal chondrosarcoma: tumor manipulation or self-seeding
Abstract Background Primary sternal chondrosarcoma, although rare, is the most common malignant tumor of the sternum. The gold standard treatment is complete surgical excision, which frequently causes the instability of the thorax necessitating future reconstruction. Local recurrence is common incre...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2023-04-01
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| Series: | Journal of Cardiothoracic Surgery |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13019-023-02213-5 |
| _version_ | 1827970305188954112 |
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| author | Riad Abdel Jalil Farah A. Abdallah |
| author_facet | Riad Abdel Jalil Farah A. Abdallah |
| author_sort | Riad Abdel Jalil |
| collection | DOAJ |
| description | Abstract Background Primary sternal chondrosarcoma, although rare, is the most common malignant tumor of the sternum. The gold standard treatment is complete surgical excision, which frequently causes the instability of the thorax necessitating future reconstruction. Local recurrence is common increasing the risk of distant metastasis. Case presentation A 60-year-old male patient was diagnosed with primary sternum chondrosarcoma and underwent surgical excision with negative resection margins. Later, he was found to have two local recurrences at 11 months and 37 months post initial excision. The two recurrences were surgically removed followed by local adjuvant radiation. Conclusion The seeding theories have been reported more frequently with relation to diagnostic biopsy procedures, tumor manipulation and self-seeding tumors. The patient developed two local recurrences despite total resection with negative margins, without concerns regarding seeding in distant metastasis. |
| first_indexed | 2024-04-09T18:51:48Z |
| format | Article |
| id | doaj.art-8b3900ff3e424bfe8d47deb53ddcef20 |
| institution | Directory Open Access Journal |
| issn | 1749-8090 |
| language | English |
| last_indexed | 2024-04-09T18:51:48Z |
| publishDate | 2023-04-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Cardiothoracic Surgery |
| spelling | doaj.art-8b3900ff3e424bfe8d47deb53ddcef202023-04-09T11:26:41ZengBMCJournal of Cardiothoracic Surgery1749-80902023-04-011811510.1186/s13019-023-02213-5Multiple local recurrences of primary sternal chondrosarcoma: tumor manipulation or self-seedingRiad Abdel Jalil0Farah A. Abdallah1Department of Thoracic Oncology, King Hussein Cancer CenterDepartment of Research, King Hussein Cancer CenterAbstract Background Primary sternal chondrosarcoma, although rare, is the most common malignant tumor of the sternum. The gold standard treatment is complete surgical excision, which frequently causes the instability of the thorax necessitating future reconstruction. Local recurrence is common increasing the risk of distant metastasis. Case presentation A 60-year-old male patient was diagnosed with primary sternum chondrosarcoma and underwent surgical excision with negative resection margins. Later, he was found to have two local recurrences at 11 months and 37 months post initial excision. The two recurrences were surgically removed followed by local adjuvant radiation. Conclusion The seeding theories have been reported more frequently with relation to diagnostic biopsy procedures, tumor manipulation and self-seeding tumors. The patient developed two local recurrences despite total resection with negative margins, without concerns regarding seeding in distant metastasis.https://doi.org/10.1186/s13019-023-02213-5ChondrosarcomaSternumLocal recurrenceSeeding |
| spellingShingle | Riad Abdel Jalil Farah A. Abdallah Multiple local recurrences of primary sternal chondrosarcoma: tumor manipulation or self-seeding Journal of Cardiothoracic Surgery Chondrosarcoma Sternum Local recurrence Seeding |
| title | Multiple local recurrences of primary sternal chondrosarcoma: tumor manipulation or self-seeding |
| title_full | Multiple local recurrences of primary sternal chondrosarcoma: tumor manipulation or self-seeding |
| title_fullStr | Multiple local recurrences of primary sternal chondrosarcoma: tumor manipulation or self-seeding |
| title_full_unstemmed | Multiple local recurrences of primary sternal chondrosarcoma: tumor manipulation or self-seeding |
| title_short | Multiple local recurrences of primary sternal chondrosarcoma: tumor manipulation or self-seeding |
| title_sort | multiple local recurrences of primary sternal chondrosarcoma tumor manipulation or self seeding |
| topic | Chondrosarcoma Sternum Local recurrence Seeding |
| url | https://doi.org/10.1186/s13019-023-02213-5 |
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