Physical Exercise Improves Cognitive Function Together with Microglia Phenotype Modulation and Remyelination in Chronic Cerebral Hypoperfusion

Physical Exercise Improves Cognitive Function Together with Microglia Phenotype Modulation and Remyelination in Chronic Cerebral Hypoperfusion

Myelin is closely associated with cognitive function and is extremely vulnerable to damage in ischemic cerebrovascular diseases. The failure of remyelination is mainly due to limitations in oligodendrocyte progenitor cells (OPCs) differentiation in the damaged area. Previous studies have shown that...

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Bibliographic Details
Main Authors:	Ting Jiang, Liying Zhang, Xiaona Pan, Haiqing Zheng, Xi Chen, Lili Li, Jing Luo, Xiquan Hu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-12-01
Series:	Frontiers in Cellular Neuroscience
Subjects:	physical exercise vascular cognitive impairment remyelination M2 microglia CX3CL1/CX3CR1 axis
Online Access:	http://journal.frontiersin.org/article/10.3389/fncel.2017.00404/full

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