Single-cell transcriptomics uncovers EGFR signaling-mediated gastric progenitor cell differentiation in stomach homeostasis
Abstract Defects in gastric progenitor cell differentiation are associated with various gastric disorders, including atrophic gastritis, intestinal metaplasia, and gastric cancer. However, the mechanisms underlying the multilineage differentiation of gastric progenitor cells during healthy homeostas...
Main Authors: | Hitomi Takada, Yohei Sasagawa, Mika Yoshimura, Kaori Tanaka, Yoshimi Iwayama, Tetsutaro Hayashi, Ayako Isomura-Matoba, Itoshi Nikaido, Akira Kurisaki |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-06-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-39113-0 |
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