Enhanced antiviral immunity and dampened inflammation in llama lymph nodes upon MERS-CoV sensing: bridging innate and adaptive cellular immune responses in camelid reservoirs

Enhanced antiviral immunity and dampened inflammation in llama lymph nodes upon MERS-CoV sensing: bridging innate and adaptive cellular immune responses in camelid reservoirs

Middle East respiratory syndrome coronavirus (MERS-CoV) infection can cause fatal pulmonary inflammatory disease in humans. Contrarily, camelids and bats are the main reservoir hosts, tolerant for MERS-CoV replication without suffering clinical disease. Here, we isolated cervical lymph node (LN) cel...

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Bibliographic Details
Main Authors: Jordi Rodon, Nigeer Te, Joaquim Segalés, Júlia Vergara-Alert, Albert Bensaid
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Immunology
Subjects:
camelids
cytokines
immune responses
llama
lymph node
lymphocyte
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1205080/full

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