Regional Differences in Uptake of Vaccination against COVID-19 and Influenza in Germany: Results from the DigiHero Cohort

During the COVID-19 pandemic in Germany, vaccination uptake exhibited considerable regional disparities. To assess the factors contributing to this variation, we examined the association of sociodemographic variables with COVID-19, COVID-19 booster, and influenza vaccination status within a cohort o...

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Main Authors: Bianca Klee, Sophie Diexer, Myka Harun Sarajan, Nadine Glaser, Mascha Binder, Thomas Frese, Matthias Girndt, Daniel Sedding, Jessica I. Hoell, Irene Moor, Michael Gekle, Rafael Mikolajczyk, Cornelia Gottschick
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/11/11/1640
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author Bianca Klee
Sophie Diexer
Myka Harun Sarajan
Nadine Glaser
Mascha Binder
Thomas Frese
Matthias Girndt
Daniel Sedding
Jessica I. Hoell
Irene Moor
Michael Gekle
Rafael Mikolajczyk
Cornelia Gottschick
author_facet Bianca Klee
Sophie Diexer
Myka Harun Sarajan
Nadine Glaser
Mascha Binder
Thomas Frese
Matthias Girndt
Daniel Sedding
Jessica I. Hoell
Irene Moor
Michael Gekle
Rafael Mikolajczyk
Cornelia Gottschick
author_sort Bianca Klee
collection DOAJ
description During the COVID-19 pandemic in Germany, vaccination uptake exhibited considerable regional disparities. To assess the factors contributing to this variation, we examined the association of sociodemographic variables with COVID-19, COVID-19 booster, and influenza vaccination status within a cohort of 37,078 participants from 13 German federal states in the digital health cohort study commonly known as DigiHero. Our findings revealed variations in vaccination rates based on sociodemographic factors. However, these factors had limited explanatory power regarding regional differences in vaccine uptake. In contrast, we found substantial correlations between regional support of specific parties during the last local elections and the vaccination uptake at the level of each administrative district. In conclusion, sociodemographic factors alone did not suffice to explain the regional disparities in vaccine uptake. Political stances can play a major role, although the current investigation did not assess individual political orientations but rather used only an ecological approach.
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spelling doaj.art-8b3fcd42869d46b1bbfd5b739c9eacf52023-11-24T15:09:54ZengMDPI AGVaccines2076-393X2023-10-011111164010.3390/vaccines11111640Regional Differences in Uptake of Vaccination against COVID-19 and Influenza in Germany: Results from the DigiHero CohortBianca Klee0Sophie Diexer1Myka Harun Sarajan2Nadine Glaser3Mascha Binder4Thomas Frese5Matthias Girndt6Daniel Sedding7Jessica I. Hoell8Irene Moor9Michael Gekle10Rafael Mikolajczyk11Cornelia Gottschick12Institute for Medical Epidemiology, Biometry and Informatics (IMEBI), Interdisciplinary Centre for Health Sciences, Medical Faculty of the Martin Luther University Halle-Wittenberg, Magdeburger Str. 8, 06112 Halle (Saale), GermanyInstitute for Medical Epidemiology, Biometry and Informatics (IMEBI), Interdisciplinary Centre for Health Sciences, Medical Faculty of the Martin Luther University Halle-Wittenberg, Magdeburger Str. 8, 06112 Halle (Saale), GermanyInstitute for Medical Epidemiology, Biometry and Informatics (IMEBI), Interdisciplinary Centre for Health Sciences, Medical Faculty of the Martin Luther University Halle-Wittenberg, Magdeburger Str. 8, 06112 Halle (Saale), GermanyInstitute for Medical Epidemiology, Biometry and Informatics (IMEBI), Interdisciplinary Centre for Health Sciences, Medical Faculty of the Martin Luther University Halle-Wittenberg, Magdeburger Str. 8, 06112 Halle (Saale), GermanyDepartment of Internal Medicine IV, Oncology/Haematology, Martin Luther University Halle-Wittenberg, Ernst-Grube-Str. 40, 06120 Halle (Saale), GermanyInstitute of General Practice and Family Medicine, Interdisciplinary Centre for Health Sciences, Medical Faculty of the Martin Luther University Halle-Wittenberg, Magdeburger Str. 8, 06112 Halle (Saale), GermanyDepartment of Internal Medicine II, Martin Luther University Halle-Wittenberg, Ernst-Grube-Str. 40, 06120 Halle (Saale), GermanyMid-German Heart Centre, Department of Cardiology and Intensive Care Medicine, University Hospital, Martin Luther University Halle-Wittenberg, Ernst-Grube-Str. 40, 06120 Halle (Saale), GermanyPaediatric Haematology and Oncology, Martin Luther University Halle-Wittenberg, Ernst-Grube-Str. 40, 06120 Halle (Saale), GermanyInstitute for Medical Sociology, Martin Luther University Halle-Wittenberg, Magdeburger Str. 8, 06112 Halle (Saale), GermanyJulius-Bernstein-Institute of Physiology, Medical Faculty of the Martin Luther University Halle-Wittenberg, Magdeburger Str. 6, 06110 Halle (Saale), GermanyInstitute for Medical Epidemiology, Biometry and Informatics (IMEBI), Interdisciplinary Centre for Health Sciences, Medical Faculty of the Martin Luther University Halle-Wittenberg, Magdeburger Str. 8, 06112 Halle (Saale), GermanyInstitute for Medical Epidemiology, Biometry and Informatics (IMEBI), Interdisciplinary Centre for Health Sciences, Medical Faculty of the Martin Luther University Halle-Wittenberg, Magdeburger Str. 8, 06112 Halle (Saale), GermanyDuring the COVID-19 pandemic in Germany, vaccination uptake exhibited considerable regional disparities. To assess the factors contributing to this variation, we examined the association of sociodemographic variables with COVID-19, COVID-19 booster, and influenza vaccination status within a cohort of 37,078 participants from 13 German federal states in the digital health cohort study commonly known as DigiHero. Our findings revealed variations in vaccination rates based on sociodemographic factors. However, these factors had limited explanatory power regarding regional differences in vaccine uptake. In contrast, we found substantial correlations between regional support of specific parties during the last local elections and the vaccination uptake at the level of each administrative district. In conclusion, sociodemographic factors alone did not suffice to explain the regional disparities in vaccine uptake. Political stances can play a major role, although the current investigation did not assess individual political orientations but rather used only an ecological approach.https://www.mdpi.com/2076-393X/11/11/1640COVID-19influenzavaccine hesitancy
spellingShingle Bianca Klee
Sophie Diexer
Myka Harun Sarajan
Nadine Glaser
Mascha Binder
Thomas Frese
Matthias Girndt
Daniel Sedding
Jessica I. Hoell
Irene Moor
Michael Gekle
Rafael Mikolajczyk
Cornelia Gottschick
Regional Differences in Uptake of Vaccination against COVID-19 and Influenza in Germany: Results from the DigiHero Cohort
Vaccines
COVID-19
influenza
vaccine hesitancy
title Regional Differences in Uptake of Vaccination against COVID-19 and Influenza in Germany: Results from the DigiHero Cohort
title_full Regional Differences in Uptake of Vaccination against COVID-19 and Influenza in Germany: Results from the DigiHero Cohort
title_fullStr Regional Differences in Uptake of Vaccination against COVID-19 and Influenza in Germany: Results from the DigiHero Cohort
title_full_unstemmed Regional Differences in Uptake of Vaccination against COVID-19 and Influenza in Germany: Results from the DigiHero Cohort
title_short Regional Differences in Uptake of Vaccination against COVID-19 and Influenza in Germany: Results from the DigiHero Cohort
title_sort regional differences in uptake of vaccination against covid 19 and influenza in germany results from the digihero cohort
topic COVID-19
influenza
vaccine hesitancy
url https://www.mdpi.com/2076-393X/11/11/1640
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