In vitro evaluation of cytotoxicity and oxidative damage induced by ochratoxin A and aflatoxin B1: protective role of antioxidants

In animal nutrition, mycotoxins are important feed contaminants. Among them, ochratoxins (OTA) and aflatoxins (AF) have several biological activities, including acute toxicity, teratogenicity, mutagenicity, immunotoxicity and carcinogenicity (Creepy, 2002). Obviously, toxicity of mycotoxins is a ris...

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Main Authors: F. Cheli, B. Bertasi, E. Pavoni, R. Rebucci, N. Losio, L. Sangalli, E. Fusi, A. Baldi
Format: Article
Language:English
Published: Taylor & Francis Group 2011-03-01
Series:Italian Journal of Animal Science
Subjects:
Online Access:http://www.aspajournal.it/index.php/ijas/article/view/2008
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author F. Cheli
B. Bertasi
E. Pavoni
R. Rebucci
N. Losio
L. Sangalli
E. Fusi
A. Baldi
author_facet F. Cheli
B. Bertasi
E. Pavoni
R. Rebucci
N. Losio
L. Sangalli
E. Fusi
A. Baldi
author_sort F. Cheli
collection DOAJ
description In animal nutrition, mycotoxins are important feed contaminants. Among them, ochratoxins (OTA) and aflatoxins (AF) have several biological activities, including acute toxicity, teratogenicity, mutagenicity, immunotoxicity and carcinogenicity (Creepy, 2002). Obviously, toxicity of mycotoxins is a risk factor not only for animals but for humans, too (Hussein et al., 2001). Deficiencies of certain nutritional factors e.g. micronutrients may predispose or enhance individuals to the toxic effects of mycotoxins (Atroshi et al., 2002). It is well known that antioxidants like vitamin E, protect cellular membranes from oxidative damage.........
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spelling doaj.art-8b40233a25b34d3380cf8a903ee5e80c2022-12-22T00:26:46ZengTaylor & Francis GroupItalian Journal of Animal Science1594-40771828-051X2011-03-0121S23123310.4081/ijas.2003.s1.231In vitro evaluation of cytotoxicity and oxidative damage induced by ochratoxin A and aflatoxin B1: protective role of antioxidantsF. CheliB. BertasiE. PavoniR. RebucciN. LosioL. SangalliE. FusiA. BaldiIn animal nutrition, mycotoxins are important feed contaminants. Among them, ochratoxins (OTA) and aflatoxins (AF) have several biological activities, including acute toxicity, teratogenicity, mutagenicity, immunotoxicity and carcinogenicity (Creepy, 2002). Obviously, toxicity of mycotoxins is a risk factor not only for animals but for humans, too (Hussein et al., 2001). Deficiencies of certain nutritional factors e.g. micronutrients may predispose or enhance individuals to the toxic effects of mycotoxins (Atroshi et al., 2002). It is well known that antioxidants like vitamin E, protect cellular membranes from oxidative damage.........http://www.aspajournal.it/index.php/ijas/article/view/2008cytotoxicity, mycotoxins, antioxidants, ROS
spellingShingle F. Cheli
B. Bertasi
E. Pavoni
R. Rebucci
N. Losio
L. Sangalli
E. Fusi
A. Baldi
In vitro evaluation of cytotoxicity and oxidative damage induced by ochratoxin A and aflatoxin B1: protective role of antioxidants
Italian Journal of Animal Science
cytotoxicity, mycotoxins, antioxidants, ROS
title In vitro evaluation of cytotoxicity and oxidative damage induced by ochratoxin A and aflatoxin B1: protective role of antioxidants
title_full In vitro evaluation of cytotoxicity and oxidative damage induced by ochratoxin A and aflatoxin B1: protective role of antioxidants
title_fullStr In vitro evaluation of cytotoxicity and oxidative damage induced by ochratoxin A and aflatoxin B1: protective role of antioxidants
title_full_unstemmed In vitro evaluation of cytotoxicity and oxidative damage induced by ochratoxin A and aflatoxin B1: protective role of antioxidants
title_short In vitro evaluation of cytotoxicity and oxidative damage induced by ochratoxin A and aflatoxin B1: protective role of antioxidants
title_sort in vitro evaluation of cytotoxicity and oxidative damage induced by ochratoxin a and aflatoxin b1 protective role of antioxidants
topic cytotoxicity, mycotoxins, antioxidants, ROS
url http://www.aspajournal.it/index.php/ijas/article/view/2008
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