Isolation of Chlamydia trachomatis or Ureaplasma urealyticum from the synovial fluid of patients with Reiter's syndrome
Background. The aim of this study was to contribute to the insight of the role of the infectious agent in ethiopathogenesis of the Reiter’s syndrome development, which could directly influence the choise of treatment of these patients. Methods. Eighteen patients with urogenital form of the Reiter’s...
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| Format: | Article |
| Language: | English |
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Military Health Department, Ministry of Defance, Serbia
2003-01-01
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| Series: | Vojnosanitetski Pregled |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2003/0042-84500301005P.pdf |
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| author | Pavlica Ljiljana Drašković Nada Kuljić-Kapulica Nada Nikolić Dragan |
| author_facet | Pavlica Ljiljana Drašković Nada Kuljić-Kapulica Nada Nikolić Dragan |
| author_sort | Pavlica Ljiljana |
| collection | DOAJ |
| description | Background. The aim of this study was to contribute to the insight of the role of the infectious agent in ethiopathogenesis of the Reiter’s syndrome development, which could directly influence the choise of treatment of these patients. Methods. Eighteen patients with urogenital form of the Reiter’s syndrome and 16 controls (6 with rheumatoid arthritis and 10 with pigmented villonodular synovitis) were included in the study. In all patients standard laboratory analyses of the blood, urine and stool were made; antibody titer to Chlamydia trachomatis and Ureaplasma urealyticum was determined in synovial fluid and serum; isolation of Chlamydia trachomatis and Ureaplasma urealyticum in urethral, cervical and conjunctival swabs, as well as in prostatic and synovial fluid, was also made. HLA typing was done, too. Chlamydia was isolated in the McCoy cell culture treated with cycloheximide while Ureaplasma was identified according to its biochemical properties grown on cell-free liquid medium. Results. Chlamydia trachomatis was isolated from the synovial fluid of 4 patients with Reiter's syndrome 22.2%), while Ureaplasma urealyticum was isolated in 7 of them (38.9%). These microorganisms were not found in any synovial fluid of the control group patients. Conclusion. Presence of these bacteria in the inflamed joint might be an important factor in etiopathogenesis of this disease, and it supports the hypothesis that arthritis in Reiter's syndrome is probably of the infectious origin. |
| first_indexed | 2024-12-13T17:12:18Z |
| format | Article |
| id | doaj.art-8b4346525e364fa8a8776800f8b05f5d |
| institution | Directory Open Access Journal |
| issn | 0042-8450 |
| language | English |
| last_indexed | 2024-12-13T17:12:18Z |
| publishDate | 2003-01-01 |
| publisher | Military Health Department, Ministry of Defance, Serbia |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj.art-8b4346525e364fa8a8776800f8b05f5d2022-12-21T23:37:30ZengMilitary Health Department, Ministry of Defance, SerbiaVojnosanitetski Pregled0042-84502003-01-0160151010.2298/VSP0301005PIsolation of Chlamydia trachomatis or Ureaplasma urealyticum from the synovial fluid of patients with Reiter's syndromePavlica LjiljanaDrašković NadaKuljić-Kapulica NadaNikolić DraganBackground. The aim of this study was to contribute to the insight of the role of the infectious agent in ethiopathogenesis of the Reiter’s syndrome development, which could directly influence the choise of treatment of these patients. Methods. Eighteen patients with urogenital form of the Reiter’s syndrome and 16 controls (6 with rheumatoid arthritis and 10 with pigmented villonodular synovitis) were included in the study. In all patients standard laboratory analyses of the blood, urine and stool were made; antibody titer to Chlamydia trachomatis and Ureaplasma urealyticum was determined in synovial fluid and serum; isolation of Chlamydia trachomatis and Ureaplasma urealyticum in urethral, cervical and conjunctival swabs, as well as in prostatic and synovial fluid, was also made. HLA typing was done, too. Chlamydia was isolated in the McCoy cell culture treated with cycloheximide while Ureaplasma was identified according to its biochemical properties grown on cell-free liquid medium. Results. Chlamydia trachomatis was isolated from the synovial fluid of 4 patients with Reiter's syndrome 22.2%), while Ureaplasma urealyticum was isolated in 7 of them (38.9%). These microorganisms were not found in any synovial fluid of the control group patients. Conclusion. Presence of these bacteria in the inflamed joint might be an important factor in etiopathogenesis of this disease, and it supports the hypothesis that arthritis in Reiter's syndrome is probably of the infectious origin.http://www.doiserbia.nb.rs/img/doi/0042-8450/2003/0042-84500301005P.pdfReiter diseasesynovial fluidChlamydia trachomatisUreaplasma urealyticumbacteriological techniques |
| spellingShingle | Pavlica Ljiljana Drašković Nada Kuljić-Kapulica Nada Nikolić Dragan Isolation of Chlamydia trachomatis or Ureaplasma urealyticum from the synovial fluid of patients with Reiter's syndrome Vojnosanitetski Pregled Reiter disease synovial fluid Chlamydia trachomatis Ureaplasma urealyticum bacteriological techniques |
| title | Isolation of Chlamydia trachomatis or Ureaplasma urealyticum from the synovial fluid of patients with Reiter's syndrome |
| title_full | Isolation of Chlamydia trachomatis or Ureaplasma urealyticum from the synovial fluid of patients with Reiter's syndrome |
| title_fullStr | Isolation of Chlamydia trachomatis or Ureaplasma urealyticum from the synovial fluid of patients with Reiter's syndrome |
| title_full_unstemmed | Isolation of Chlamydia trachomatis or Ureaplasma urealyticum from the synovial fluid of patients with Reiter's syndrome |
| title_short | Isolation of Chlamydia trachomatis or Ureaplasma urealyticum from the synovial fluid of patients with Reiter's syndrome |
| title_sort | isolation of chlamydia trachomatis or ureaplasma urealyticum from the synovial fluid of patients with reiter s syndrome |
| topic | Reiter disease synovial fluid Chlamydia trachomatis Ureaplasma urealyticum bacteriological techniques |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2003/0042-84500301005P.pdf |
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