HIF-1α accumulation in response to transient hypoglycemia may worsen diabetic eye disease

HIF-1α accumulation in response to transient hypoglycemia may worsen diabetic eye disease

Summary: Tight glycemic control (TGC), the cornerstone of diabetic management, reduces the incidence and progression of diabetic microvascular disease. However, TGC can also lead to transient episodes of hypoglycemia, which have been associated with adverse outcomes in patients with diabetes. Here,...

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Bibliographic Details
Main Authors: Chuanyu Guo, Monika Deshpande, Yueqi Niu, Isha Kachwala, Miguel Flores-Bellver, Haley Megarity, Taylor Nuse, Savalan Babapoor-Farrokhran, Michael Ramada, Jaron Sanchez, Neelay Inamdar, Thomas V. Johnson, Maria Valeria Canto-Soler, Silvia Montaner, Akrit Sodhi
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Cell Reports
Subjects:
CP: Cell biology
CP: Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124722018800

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