A Custom DNA-Based NGS Panel for the Molecular Characterization of Patients With Diffuse Gliomas: Diagnostic and Therapeutic Applications

A Custom DNA-Based NGS Panel for the Molecular Characterization of Patients With Diffuse Gliomas: Diagnostic and Therapeutic Applications

The management of patients with Central Nervous System (CNS) malignancies relies on the appropriate classification of these tumors. Recently, the World Health Organization (WHO) has published new criteria underlining the importance of an accurate molecular characterization of CNS malignancies, in or...

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Bibliographic Details
Main Authors: Elena Tirrò, Michele Massimino, Giuseppe Broggi, Chiara Romano, Simone Minasi, Francesca Gianno, Manila Antonelli, Gianmarco Motta, Francesco Certo, Roberto Altieri, Livia Manzella, Rosario Caltabiano, Giuseppe Maria Vincenzo Barbagallo, Francesca Romana Buttarelli, Gaetano Magro, Felice Giangaspero, Paolo Vigneri
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Oncology
Subjects:
glioma
next generation sequencing
biomarkers
molecular biology
diagnosis
targeted therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.861078/full

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