Vulvovaginal Candidosis: Current Concepts, Challenges and Perspectives

Vulvovaginal candidosis (VVC) is a frequently occurring infection of the lower female genital tract, mostly affecting immuno-competent women at childbearing age. <i>Candida albicans</i> is the most prevalent pathogenic yeast—apart from other non-<i>albicans</i> species—relate...

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Main Authors: Valentina Sustr, Philipp Foessleitner, Herbert Kiss, Alex Farr
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Journal of Fungi
Subjects:
Online Access:https://www.mdpi.com/2309-608X/6/4/267
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author Valentina Sustr
Philipp Foessleitner
Herbert Kiss
Alex Farr
author_facet Valentina Sustr
Philipp Foessleitner
Herbert Kiss
Alex Farr
author_sort Valentina Sustr
collection DOAJ
description Vulvovaginal candidosis (VVC) is a frequently occurring infection of the lower female genital tract, mostly affecting immuno-competent women at childbearing age. <i>Candida albicans</i> is the most prevalent pathogenic yeast—apart from other non-<i>albicans</i> species—related to this fungal infection. Different virulence factors of <i>C. albicans</i> have been identified, which increase the risk of developing VVC. To initiate treatment and positively influence the disease course, fast and reliable diagnosis is crucial. In this narrative review, we cover the existing state of understanding of the epidemiology, pathogenesis and diagnosis of VVC. However, treatment recommendations should follow current guidelines.
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spelling doaj.art-8b4db7be4e4249a2b323be49ce8a1cd02023-11-20T20:07:20ZengMDPI AGJournal of Fungi2309-608X2020-11-016426710.3390/jof6040267Vulvovaginal Candidosis: Current Concepts, Challenges and PerspectivesValentina Sustr0Philipp Foessleitner1Herbert Kiss2Alex Farr3Department of Obstetrics and Gynecology, Division of Obstetrics and Feto-Maternal Medicine, Medical University of Vienna, Waehringer Guertel 18–20, A-1090 Vienna, AustriaDepartment of Obstetrics and Gynecology, Division of Obstetrics and Feto-Maternal Medicine, Medical University of Vienna, Waehringer Guertel 18–20, A-1090 Vienna, AustriaDepartment of Obstetrics and Gynecology, Division of Obstetrics and Feto-Maternal Medicine, Medical University of Vienna, Waehringer Guertel 18–20, A-1090 Vienna, AustriaDepartment of Obstetrics and Gynecology, Division of Obstetrics and Feto-Maternal Medicine, Medical University of Vienna, Waehringer Guertel 18–20, A-1090 Vienna, AustriaVulvovaginal candidosis (VVC) is a frequently occurring infection of the lower female genital tract, mostly affecting immuno-competent women at childbearing age. <i>Candida albicans</i> is the most prevalent pathogenic yeast—apart from other non-<i>albicans</i> species—related to this fungal infection. Different virulence factors of <i>C. albicans</i> have been identified, which increase the risk of developing VVC. To initiate treatment and positively influence the disease course, fast and reliable diagnosis is crucial. In this narrative review, we cover the existing state of understanding of the epidemiology, pathogenesis and diagnosis of VVC. However, treatment recommendations should follow current guidelines.https://www.mdpi.com/2309-608X/6/4/267<i>Candida albicans</i>diagnosisepidemiologyfungal infectionreviewvulvovaginal candidosis
spellingShingle Valentina Sustr
Philipp Foessleitner
Herbert Kiss
Alex Farr
Vulvovaginal Candidosis: Current Concepts, Challenges and Perspectives
Journal of Fungi
<i>Candida albicans</i>
diagnosis
epidemiology
fungal infection
review
vulvovaginal candidosis
title Vulvovaginal Candidosis: Current Concepts, Challenges and Perspectives
title_full Vulvovaginal Candidosis: Current Concepts, Challenges and Perspectives
title_fullStr Vulvovaginal Candidosis: Current Concepts, Challenges and Perspectives
title_full_unstemmed Vulvovaginal Candidosis: Current Concepts, Challenges and Perspectives
title_short Vulvovaginal Candidosis: Current Concepts, Challenges and Perspectives
title_sort vulvovaginal candidosis current concepts challenges and perspectives
topic <i>Candida albicans</i>
diagnosis
epidemiology
fungal infection
review
vulvovaginal candidosis
url https://www.mdpi.com/2309-608X/6/4/267
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AT alexfarr vulvovaginalcandidosiscurrentconceptschallengesandperspectives