Evaluation of anterior mediastinal solid tumors by CT perfusion: a preliminary study
PURPOSE:We aimed to assess the role of computed tomography (CT) perfusion in differentiation of thymoma from thymic hyperplasia, lymphoma, thymic carcinoma, and lung cancer invading anterior mediastinum.METHODS:In this study, 25 patients with an anterior mediastinal lesion underwent CT perfusion ima...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Galenos Publishing House
2017-01-01
|
| Series: | Diagnostic and Interventional Radiology |
| Online Access: |
http://www.dirjournal.org/archives/archive-detail/article-preview/evaluation-of-anterior-mediastinal-solid-tumors-by/55354
|
| _version_ | 1827823379120390144 |
|---|---|
| author | Selim Bakan Sedat Giray Kandemirli Atilla Süleyman Dikici Ezel Erşen Onur Yıldırım Cesur Samancı Şebnem Batur Deniz Çebi Olgun Fatih Kantarcı Canan Akman |
| author_facet | Selim Bakan Sedat Giray Kandemirli Atilla Süleyman Dikici Ezel Erşen Onur Yıldırım Cesur Samancı Şebnem Batur Deniz Çebi Olgun Fatih Kantarcı Canan Akman |
| author_sort | Selim Bakan |
| collection | DOAJ |
| description | PURPOSE:We aimed to assess the role of computed tomography (CT) perfusion in differentiation of thymoma from thymic hyperplasia, lymphoma, thymic carcinoma, and lung cancer invading anterior mediastinum.METHODS:In this study, 25 patients with an anterior mediastinal lesion underwent CT perfusion imaging from January 2015 to February 2016. Diagnoses included thymoma (n=7), thymic hyperplasia (n=8), lymphoma (n=4), thymic carcinoma (n=3), and invasive lung cancer (n=3). Lymphoma, thymic carcinoma, and lung cancer were grouped as malignant tumors for statistical analysis. Values for blood flow, blood volume, and permeability surface were measured in CT perfusion.RESULTS:Blood flow and blood volume values were higher in thymoma in comparison to thymic hyperplasia; however, the difference was not statistically significant. Blood volume values were significantly higher in thymoma (mean, 11.4 mL/100 mL; range, 5.2–20.2 mL/100 mL) compared with lymphoma (mean, 5.3 mL/100 mL; range, 2.5–7.2 mL/100 mL) (P = 0.023). Blood flow and blood volume values were significantly higher in thymoma compared with non-thymoma malignant tumors (P = 0.025).CONCLUSION:CT perfusion is helpful in differentiating thymoma from non-thymoma malignancies including lymphoma, thymic carcinoma, and invasive lung cancer involving the anterior mediastinum. |
| first_indexed | 2024-03-12T02:10:15Z |
| format | Article |
| id | doaj.art-8b4e5207cdde4b7a8e9393a181bbea5f |
| institution | Directory Open Access Journal |
| issn | 1305-3825 1305-3612 |
| language | English |
| last_indexed | 2024-03-12T02:10:15Z |
| publishDate | 2017-01-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Diagnostic and Interventional Radiology |
| spelling | doaj.art-8b4e5207cdde4b7a8e9393a181bbea5f2023-09-06T13:29:34ZengGalenos Publishing HouseDiagnostic and Interventional Radiology1305-38251305-36122017-01-01231101410.5152/dir.2016.1609313049054Evaluation of anterior mediastinal solid tumors by CT perfusion: a preliminary studySelim Bakan0Sedat Giray Kandemirli1Atilla Süleyman Dikici2Ezel Erşen3Onur Yıldırım4Cesur Samancı5Şebnem Batur6Deniz Çebi Olgun7Fatih Kantarcı8Canan Akman9 Department of Radiology, İstanbul University Cerrahpaşa School of Medicine, İstanbul, Turkey Department of Radiology, İstanbul University Cerrahpaşa School of Medicine, İstanbul, Turkey Department of Radiology, İstanbul University Cerrahpaşa School of Medicine, İstanbul, Turkey Department of Thoracic Surgery, İstanbul University Cerrahpaşa School of Medicine, İstanbul, Turkey Department of Radiology, İstanbul University Cerrahpaşa School of Medicine, İstanbul, Turkey Department of Radiology, İstanbul University Cerrahpaşa School of Medicine, İstanbul, Turkey Department of Pathology, İstanbul University Cerrahpaşa School of Medicine, İstanbul, Turkey Department of Radiology, İstanbul University Cerrahpaşa School of Medicine, İstanbul, Turkey Department of Radiology, İstanbul University Cerrahpaşa School of Medicine, İstanbul, Turkey Department of Radiology, İstanbul University Cerrahpaşa School of Medicine, İstanbul, Turkey PURPOSE:We aimed to assess the role of computed tomography (CT) perfusion in differentiation of thymoma from thymic hyperplasia, lymphoma, thymic carcinoma, and lung cancer invading anterior mediastinum.METHODS:In this study, 25 patients with an anterior mediastinal lesion underwent CT perfusion imaging from January 2015 to February 2016. Diagnoses included thymoma (n=7), thymic hyperplasia (n=8), lymphoma (n=4), thymic carcinoma (n=3), and invasive lung cancer (n=3). Lymphoma, thymic carcinoma, and lung cancer were grouped as malignant tumors for statistical analysis. Values for blood flow, blood volume, and permeability surface were measured in CT perfusion.RESULTS:Blood flow and blood volume values were higher in thymoma in comparison to thymic hyperplasia; however, the difference was not statistically significant. Blood volume values were significantly higher in thymoma (mean, 11.4 mL/100 mL; range, 5.2–20.2 mL/100 mL) compared with lymphoma (mean, 5.3 mL/100 mL; range, 2.5–7.2 mL/100 mL) (P = 0.023). Blood flow and blood volume values were significantly higher in thymoma compared with non-thymoma malignant tumors (P = 0.025).CONCLUSION:CT perfusion is helpful in differentiating thymoma from non-thymoma malignancies including lymphoma, thymic carcinoma, and invasive lung cancer involving the anterior mediastinum. http://www.dirjournal.org/archives/archive-detail/article-preview/evaluation-of-anterior-mediastinal-solid-tumors-by/55354 |
| spellingShingle | Selim Bakan Sedat Giray Kandemirli Atilla Süleyman Dikici Ezel Erşen Onur Yıldırım Cesur Samancı Şebnem Batur Deniz Çebi Olgun Fatih Kantarcı Canan Akman Evaluation of anterior mediastinal solid tumors by CT perfusion: a preliminary study Diagnostic and Interventional Radiology |
| title | Evaluation of anterior mediastinal solid tumors by CT perfusion: a preliminary study |
| title_full | Evaluation of anterior mediastinal solid tumors by CT perfusion: a preliminary study |
| title_fullStr | Evaluation of anterior mediastinal solid tumors by CT perfusion: a preliminary study |
| title_full_unstemmed | Evaluation of anterior mediastinal solid tumors by CT perfusion: a preliminary study |
| title_short | Evaluation of anterior mediastinal solid tumors by CT perfusion: a preliminary study |
| title_sort | evaluation of anterior mediastinal solid tumors by ct perfusion a preliminary study |
| url |
http://www.dirjournal.org/archives/archive-detail/article-preview/evaluation-of-anterior-mediastinal-solid-tumors-by/55354
|
| work_keys_str_mv | AT selimbakan evaluationofanteriormediastinalsolidtumorsbyctperfusionapreliminarystudy AT sedatgiraykandemirli evaluationofanteriormediastinalsolidtumorsbyctperfusionapreliminarystudy AT atillasuleymandikici evaluationofanteriormediastinalsolidtumorsbyctperfusionapreliminarystudy AT ezelersen evaluationofanteriormediastinalsolidtumorsbyctperfusionapreliminarystudy AT onuryıldırım evaluationofanteriormediastinalsolidtumorsbyctperfusionapreliminarystudy AT cesursamancı evaluationofanteriormediastinalsolidtumorsbyctperfusionapreliminarystudy AT sebnembatur evaluationofanteriormediastinalsolidtumorsbyctperfusionapreliminarystudy AT denizcebiolgun evaluationofanteriormediastinalsolidtumorsbyctperfusionapreliminarystudy AT fatihkantarcı evaluationofanteriormediastinalsolidtumorsbyctperfusionapreliminarystudy AT cananakman evaluationofanteriormediastinalsolidtumorsbyctperfusionapreliminarystudy |