The Effect of Postinduction Blood Glucose on Intraoperative Hypothermia
<i>Background and Objectives</i>: Hypothermia frequently occurs in patients undergoing surgery and is associated with adverse complications. Therefore, this study aimed to investigate the postinduction blood glucose and occurrence of intraoperative hypothermia in patients undergoing lapa...
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| Format: | Article |
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MDPI AG
2023-02-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/59/2/395 |
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| author | Zhangtian Shen Kosuke Kuroda Hiroshi Morimatsu |
| author_facet | Zhangtian Shen Kosuke Kuroda Hiroshi Morimatsu |
| author_sort | Zhangtian Shen |
| collection | DOAJ |
| description | <i>Background and Objectives</i>: Hypothermia frequently occurs in patients undergoing surgery and is associated with adverse complications. Therefore, this study aimed to investigate the postinduction blood glucose and occurrence of intraoperative hypothermia in patients undergoing laparoscopic surgery. <i>Materials and Methods</i>: This retrospective observational study included 334 patients aged ≥20 years who had undergone elective laparoscopic surgery. The primary outcome of this study was the incidence of intraoperative hypothermia. Stratified analysis revealed differences between patients with and without diabetes. <i>Results</i>: Hypothermia occurred in 200 (59.9%) patients. In multivariate analysis, out-of-range postinduction glucose was independently associated with hypothermia (>150 mg/dL: odds ratio 2.17, 95% confidence interval (1.02, 4.61), <i>p</i> = 0.045; <110 mg/dL: odds ratio 2.02, 95% confidence interval (1.15, 3.55), <i>p</i> = 0.015), whereas preoperative HbA1c >6% was not significantly associated with hypothermia (odds ratio 1.02, 95% confidence interval (0.56, 1.84), <i>p</i> = 0.961). Considering only patients with diabetes, the incidence of hypothermia was lower (<i>p</i> = 0.002), the duration of hypothermia was shorter (<i>p</i> = 0.007), and the minimum temperature was higher (<i>p</i> = 0.006) in those with a postinduction glucose level of 110–150 mg/dL. <i>Conclusions</i>: The postinduction glucose level is independently associated with intraoperative hypothermia. Out-of-range postinduction glucose appeared to have an impact on the development of hypothermia in patients with diabetes, especially those with a postinduction glucose level <110 mg/dL. |
| first_indexed | 2024-03-11T08:27:27Z |
| format | Article |
| id | doaj.art-8b5058ae4e984db49be5f3dbd93803f7 |
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| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-11T08:27:27Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-8b5058ae4e984db49be5f3dbd93803f72023-11-16T22:01:12ZengMDPI AGMedicina1010-660X1648-91442023-02-0159239510.3390/medicina59020395The Effect of Postinduction Blood Glucose on Intraoperative HypothermiaZhangtian Shen0Kosuke Kuroda1Hiroshi Morimatsu2Department of Anesthesiology and Resuscitology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kitaku, Okayama 700-8558, JapanDepartment of Anesthesiology and Resuscitology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kitaku, Okayama 700-8558, JapanDepartment of Anesthesiology and Resuscitology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kitaku, Okayama 700-8558, Japan<i>Background and Objectives</i>: Hypothermia frequently occurs in patients undergoing surgery and is associated with adverse complications. Therefore, this study aimed to investigate the postinduction blood glucose and occurrence of intraoperative hypothermia in patients undergoing laparoscopic surgery. <i>Materials and Methods</i>: This retrospective observational study included 334 patients aged ≥20 years who had undergone elective laparoscopic surgery. The primary outcome of this study was the incidence of intraoperative hypothermia. Stratified analysis revealed differences between patients with and without diabetes. <i>Results</i>: Hypothermia occurred in 200 (59.9%) patients. In multivariate analysis, out-of-range postinduction glucose was independently associated with hypothermia (>150 mg/dL: odds ratio 2.17, 95% confidence interval (1.02, 4.61), <i>p</i> = 0.045; <110 mg/dL: odds ratio 2.02, 95% confidence interval (1.15, 3.55), <i>p</i> = 0.015), whereas preoperative HbA1c >6% was not significantly associated with hypothermia (odds ratio 1.02, 95% confidence interval (0.56, 1.84), <i>p</i> = 0.961). Considering only patients with diabetes, the incidence of hypothermia was lower (<i>p</i> = 0.002), the duration of hypothermia was shorter (<i>p</i> = 0.007), and the minimum temperature was higher (<i>p</i> = 0.006) in those with a postinduction glucose level of 110–150 mg/dL. <i>Conclusions</i>: The postinduction glucose level is independently associated with intraoperative hypothermia. Out-of-range postinduction glucose appeared to have an impact on the development of hypothermia in patients with diabetes, especially those with a postinduction glucose level <110 mg/dL.https://www.mdpi.com/1648-9144/59/2/395blood glucosehemoglobin A1chypothermiathermoregulationlaparoscopytype 2 diabetes |
| spellingShingle | Zhangtian Shen Kosuke Kuroda Hiroshi Morimatsu The Effect of Postinduction Blood Glucose on Intraoperative Hypothermia Medicina blood glucose hemoglobin A1c hypothermia thermoregulation laparoscopy type 2 diabetes |
| title | The Effect of Postinduction Blood Glucose on Intraoperative Hypothermia |
| title_full | The Effect of Postinduction Blood Glucose on Intraoperative Hypothermia |
| title_fullStr | The Effect of Postinduction Blood Glucose on Intraoperative Hypothermia |
| title_full_unstemmed | The Effect of Postinduction Blood Glucose on Intraoperative Hypothermia |
| title_short | The Effect of Postinduction Blood Glucose on Intraoperative Hypothermia |
| title_sort | effect of postinduction blood glucose on intraoperative hypothermia |
| topic | blood glucose hemoglobin A1c hypothermia thermoregulation laparoscopy type 2 diabetes |
| url | https://www.mdpi.com/1648-9144/59/2/395 |
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