Nuclear envelope protein Lem2 is required for mouse development and regulates MAP and AKT kinases.

The nuclear lamina, along with associated nuclear membrane proteins, is a nexus for regulating signaling in the nucleus. Numerous human diseases arise from mutations in lamina proteins, and experimental models for these disorders have revealed aberrant regulation of various signaling pathways. Previ...

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Bibliografske podrobnosti
Main Authors: Olga Tapia, Loren G Fong, Michael D Huber, Stephen G Young, Larry Gerace
Format: Article
Jezik:English
Izdano: Public Library of Science (PLoS) 2015-01-01
Serija:PLoS ONE
Online dostop:http://europepmc.org/articles/PMC4366207?pdf=render