Potential roles of the interactions between gut microbiota and metabolites in LPS-induced intrauterine inflammation (IUI) and associated preterm birth (PTB)

Potential roles of the interactions between gut microbiota and metabolites in LPS-induced intrauterine inflammation (IUI) and associated preterm birth (PTB)

Abstract Background Prenatal exposure to intrauterine inflammation (IUI) is a crucial event in preterm birth (PTB) pathophysiology, increasing the incidence of neurodevelopmental disorders. Gut microbiota and metabolite profile alterations have been reported to be involved in PTB pathophysiology. Me...

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Bibliographic Details
Main Authors: Bei Jia, Lijun Tang, Huibing Liu, Wenqian Chen, Qian Chen, Mei Zhong, Ailan Yin
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Translational Medicine
Subjects:
Preterm birth (PTB)
Intrauterine inflammation (IUI)
Gut microbiota
Metabolites
Pyruvic acid
Online Access:https://doi.org/10.1186/s12967-023-04603-8

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