In Vitro Comparison of Biological Effects of Coe-Pak and Reso-Pac Periodontal Dressings
Objectives: The purpose of the present study was to compare the cytotoxicity of Reso-Pac and Coe-Pak periodontal dressing. Material and Methods: According to ISO-10993-12:2012, 1-, 3- and 7-day extracts of the two periodontal dressings were prepared in cell culture medium and exposed to the two c...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Stilus Optimus
2017-03-01
|
| Series: | eJournal of Oral Maxillofacial Research |
| Subjects: | |
| Online Access: | http://www.ejomr.org/JOMR/archives/2017/1/e3/v8n1e3ht.htm |
| _version_ | 1819085558899539968 |
|---|---|
| author | Mahdi Kadkhodazadeh Zahra Baghani Maryam Torshabi Bahar Basirat |
| author_facet | Mahdi Kadkhodazadeh Zahra Baghani Maryam Torshabi Bahar Basirat |
| author_sort | Mahdi Kadkhodazadeh |
| collection | DOAJ |
| description | Objectives: The purpose of the present study was to compare the cytotoxicity of Reso-Pac and Coe-Pak periodontal dressing.
Material and Methods: According to ISO-10993-12:2012, 1-, 3- and 7-day extracts of the two periodontal dressings were prepared in cell culture medium and exposed to the two cultured cell lines. Cell viability and proliferation at 24 h and 72 h following exposure were evaluated using quantitative MTT assay.
Results: The results showed a significant (P < 0.05) reduction in the viability of cells exposed to the 3- and 7-day Coe-Pak extracts at 24 h and 72 h compared to the control group (no exposure to the extract). Reso-Pac extracts slightly decreased cell viability compared to the control group. Understudy materials showed greater cytotoxicity against human osteoblast-like compared to the human gingival fibroblast cells. No significant (P > 0.05) difference was found in the viability of cells exposed to undiluted (100%) one-day extract and diluted (50%) extract of both understudy materials at 24 h and 72 h after exposure.
Conclusions: Based on the results, Reso-Pac periodontal dressing has less cytotoxicity than Coe-Pak. |
| first_indexed | 2024-12-21T21:06:16Z |
| format | Article |
| id | doaj.art-8b550f5b0a354be1a9f7363102ef564d |
| institution | Directory Open Access Journal |
| issn | 2029-283X |
| language | English |
| last_indexed | 2024-12-21T21:06:16Z |
| publishDate | 2017-03-01 |
| publisher | Stilus Optimus |
| record_format | Article |
| series | eJournal of Oral Maxillofacial Research |
| spelling | doaj.art-8b550f5b0a354be1a9f7363102ef564d2022-12-21T18:50:17ZengStilus OptimuseJournal of Oral Maxillofacial Research2029-283X2017-03-0181e310.5037/jomr.2017.8103In Vitro Comparison of Biological Effects of Coe-Pak and Reso-Pac Periodontal DressingsMahdi KadkhodazadehZahra BaghaniMaryam TorshabiBahar BasiratObjectives: The purpose of the present study was to compare the cytotoxicity of Reso-Pac and Coe-Pak periodontal dressing. Material and Methods: According to ISO-10993-12:2012, 1-, 3- and 7-day extracts of the two periodontal dressings were prepared in cell culture medium and exposed to the two cultured cell lines. Cell viability and proliferation at 24 h and 72 h following exposure were evaluated using quantitative MTT assay. Results: The results showed a significant (P < 0.05) reduction in the viability of cells exposed to the 3- and 7-day Coe-Pak extracts at 24 h and 72 h compared to the control group (no exposure to the extract). Reso-Pac extracts slightly decreased cell viability compared to the control group. Understudy materials showed greater cytotoxicity against human osteoblast-like compared to the human gingival fibroblast cells. No significant (P > 0.05) difference was found in the viability of cells exposed to undiluted (100%) one-day extract and diluted (50%) extract of both understudy materials at 24 h and 72 h after exposure. Conclusions: Based on the results, Reso-Pac periodontal dressing has less cytotoxicity than Coe-Pak.http://www.ejomr.org/JOMR/archives/2017/1/e3/v8n1e3ht.htmfibroblastsmaterials testingosteoblastsperiodontal dressings |
| spellingShingle | Mahdi Kadkhodazadeh Zahra Baghani Maryam Torshabi Bahar Basirat In Vitro Comparison of Biological Effects of Coe-Pak and Reso-Pac Periodontal Dressings eJournal of Oral Maxillofacial Research fibroblasts materials testing osteoblasts periodontal dressings |
| title | In Vitro Comparison of Biological Effects of Coe-Pak and Reso-Pac Periodontal Dressings |
| title_full | In Vitro Comparison of Biological Effects of Coe-Pak and Reso-Pac Periodontal Dressings |
| title_fullStr | In Vitro Comparison of Biological Effects of Coe-Pak and Reso-Pac Periodontal Dressings |
| title_full_unstemmed | In Vitro Comparison of Biological Effects of Coe-Pak and Reso-Pac Periodontal Dressings |
| title_short | In Vitro Comparison of Biological Effects of Coe-Pak and Reso-Pac Periodontal Dressings |
| title_sort | in vitro comparison of biological effects of coe pak and reso pac periodontal dressings |
| topic | fibroblasts materials testing osteoblasts periodontal dressings |
| url | http://www.ejomr.org/JOMR/archives/2017/1/e3/v8n1e3ht.htm |
| work_keys_str_mv | AT mahdikadkhodazadeh invitrocomparisonofbiologicaleffectsofcoepakandresopacperiodontaldressings AT zahrabaghani invitrocomparisonofbiologicaleffectsofcoepakandresopacperiodontaldressings AT maryamtorshabi invitrocomparisonofbiologicaleffectsofcoepakandresopacperiodontaldressings AT baharbasirat invitrocomparisonofbiologicaleffectsofcoepakandresopacperiodontaldressings |