REFRACTORY HYPERTENSION – MODERN APPROACHES TO DIAGNOSTICS AND TREATMENT
The refractory arterial hypertension (HT) is diagnosed, if therapy with three antihypertensive drugs from different classes (including a diuretic) in optimal doses did not provide target blood pressure (BP) level. Prevalence of a refractory HT is high and reaches up 10-30% among hypertensive patient...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Столичная издательская компания
2016-01-01
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| Series: | Рациональная фармакотерапия в кардиологии |
| Subjects: | |
| Online Access: | https://www.rpcardio.online/jour/article/view/822 |
| _version_ | 1797232305036591104 |
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| author | A. N. Britov M. M. Bystrova |
| author_facet | A. N. Britov M. M. Bystrova |
| author_sort | A. N. Britov |
| collection | DOAJ |
| description | The refractory arterial hypertension (HT) is diagnosed, if therapy with three antihypertensive drugs from different classes (including a diuretic) in optimal doses did not provide target blood pressure (BP) level. Prevalence of a refractory HT is high and reaches up 10-30% among hypertensive patients. However, poor BP control is often caused by patient non-compliance with the medical recommendations, an inadequate estimation of BP level, and "white coat" HT. It is classified as a pseudo resistance. Obesity, salt and alcohol overconsumption, taking some drugs worsen BP control. Secondary HT causes (sleep apnea syndrome, kidney diseases, renal artery stenosis, and primary hyperaldosteronism) are more possible in patients with refractory HT. Specific treatment of these diseases improves BP control and long-term prognosis. Successful treatment of refractory HT includes detection and correction of reversible risk factors and reasons of the secondary HT, use of the effective combined therapy with the aldosterone antagonist. Improvement of patient compliance is one of key factors of effective treatment. |
| first_indexed | 2024-03-08T14:04:09Z |
| format | Article |
| id | doaj.art-8b5606b6da194b67a6c63d179d376d5f |
| institution | Directory Open Access Journal |
| issn | 1819-6446 2225-3653 |
| language | English |
| last_indexed | 2024-04-24T15:58:09Z |
| publishDate | 2016-01-01 |
| publisher | Столичная издательская компания |
| record_format | Article |
| series | Рациональная фармакотерапия в кардиологии |
| spelling | doaj.art-8b5606b6da194b67a6c63d179d376d5f2024-04-01T07:43:29ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532016-01-016220621110.20996/1819-6446-2010-6-2-206-211821REFRACTORY HYPERTENSION – MODERN APPROACHES TO DIAGNOSTICS AND TREATMENTA. N. Britov0M. M. Bystrova1State Research Center for Preventive Medicine of RosmedtechnologyState Research Center for Preventive Medicine of RosmedtechnologyThe refractory arterial hypertension (HT) is diagnosed, if therapy with three antihypertensive drugs from different classes (including a diuretic) in optimal doses did not provide target blood pressure (BP) level. Prevalence of a refractory HT is high and reaches up 10-30% among hypertensive patients. However, poor BP control is often caused by patient non-compliance with the medical recommendations, an inadequate estimation of BP level, and "white coat" HT. It is classified as a pseudo resistance. Obesity, salt and alcohol overconsumption, taking some drugs worsen BP control. Secondary HT causes (sleep apnea syndrome, kidney diseases, renal artery stenosis, and primary hyperaldosteronism) are more possible in patients with refractory HT. Specific treatment of these diseases improves BP control and long-term prognosis. Successful treatment of refractory HT includes detection and correction of reversible risk factors and reasons of the secondary HT, use of the effective combined therapy with the aldosterone antagonist. Improvement of patient compliance is one of key factors of effective treatment.https://www.rpcardio.online/jour/article/view/822refractory arterial hypertensiondiagnosticstreatment |
| spellingShingle | A. N. Britov M. M. Bystrova REFRACTORY HYPERTENSION – MODERN APPROACHES TO DIAGNOSTICS AND TREATMENT Рациональная фармакотерапия в кардиологии refractory arterial hypertension diagnostics treatment |
| title | REFRACTORY HYPERTENSION – MODERN APPROACHES TO DIAGNOSTICS AND TREATMENT |
| title_full | REFRACTORY HYPERTENSION – MODERN APPROACHES TO DIAGNOSTICS AND TREATMENT |
| title_fullStr | REFRACTORY HYPERTENSION – MODERN APPROACHES TO DIAGNOSTICS AND TREATMENT |
| title_full_unstemmed | REFRACTORY HYPERTENSION – MODERN APPROACHES TO DIAGNOSTICS AND TREATMENT |
| title_short | REFRACTORY HYPERTENSION – MODERN APPROACHES TO DIAGNOSTICS AND TREATMENT |
| title_sort | refractory hypertension modern approaches to diagnostics and treatment |
| topic | refractory arterial hypertension diagnostics treatment |
| url | https://www.rpcardio.online/jour/article/view/822 |
| work_keys_str_mv | AT anbritov refractoryhypertensionmodernapproachestodiagnosticsandtreatment AT mmbystrova refractoryhypertensionmodernapproachestodiagnosticsandtreatment |