The Lectin Pathway of Complement in Myocardial Ischemia/Reperfusion Injury—Review of Its Significance and the Potential Impact of Therapeutic Interference by C1 Esterase Inhibitor

The Lectin Pathway of Complement in Myocardial Ischemia/Reperfusion Injury—Review of Its Significance and the Potential Impact of Therapeutic Interference by C1 Esterase Inhibitor

Acute myocardial infarction (AMI) remains a leading cause of morbidity and mortality in modern medicine. Early reperfusion accomplished by primary percutaneous coronary intervention is pivotal for reducing myocardial damage in ST elevation AMI. However, restoration of coronary blood flow may paradox...

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Bibliographic Details
Main Authors:	Anneza Panagiotou, Marten Trendelenburg, Michael Osthoff
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-05-01
Series:	Frontiers in Immunology
Subjects:	C1 esterase inhibitor complement system complement inhibition ischemia/reperfusion injury mannose-binding lectin myocardial infarction
Online Access:	https://www.frontiersin.org/article/10.3389/fimmu.2018.01151/full

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