Tomography and Prognostic Indices in the State of the Art of Evaluation in Hospitalized Patients with COVID-19 Pneumonia
Evaluation in medical emergencies of COVID-19 patients represents a challenge to regulate preventive and timely management. There are key imaging and laboratory tools to classify the severity. The aim of the study was to evaluate the chest CT score performance and prognostic indices in COVID-19 pati...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-11-01
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| Series: | Pathogens |
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| Online Access: | https://www.mdpi.com/2076-0817/11/11/1281 |
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| author | Sergio Críales-Vera Huitzilihuitl Saucedo-Orozco Pedro Iturralde-Torres Gustavo Martínez-Mota Estefanía Dávila-Medina Verónica Guarner-Lans Linaloe Manzano-Pech Israel Pérez-Torres María Elena Soto |
| author_facet | Sergio Críales-Vera Huitzilihuitl Saucedo-Orozco Pedro Iturralde-Torres Gustavo Martínez-Mota Estefanía Dávila-Medina Verónica Guarner-Lans Linaloe Manzano-Pech Israel Pérez-Torres María Elena Soto |
| author_sort | Sergio Críales-Vera |
| collection | DOAJ |
| description | Evaluation in medical emergencies of COVID-19 patients represents a challenge to regulate preventive and timely management. There are key imaging and laboratory tools to classify the severity. The aim of the study was to evaluate the chest CT score performance and prognostic indices in COVID-19 patients to predict the progression to critical illness. This was a retrospective study between run between April and December 2020, in which 109 patients were included. Patients of any age and gender and who required hospitalization due to a confirmed COVID-19 diagnosis by RT-PCR and chest CT and laboratory were analyzed. In 75% of them, there was at least one comorbidity, and 30% developed critical illness, and the average mortality was 10%. In 49.5%, there was a CORADS-5 on admission, and in 50%, there was a peripheral distribution of the interstitial infiltrate in the left lower lobe. The risk factors were FiO<sub>2</sub>, CT score > 18, and the NRL index. The combination of the high-risk Quick COVID-19 Severity Index (qCSI) plus CT score > 18 indices was the best prediction index for the development of a critical condition. The combined use of indices in infected COVID-19 patients showed diagnostic accuracy and predicted severity. Imaging and the laboratory tests are key tools independent of the wave of recurrence. |
| first_indexed | 2024-03-09T18:46:07Z |
| format | Article |
| id | doaj.art-8b5b689cb54a4c909003a73912dfec2d |
| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-03-09T18:46:07Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-8b5b689cb54a4c909003a73912dfec2d2023-11-24T06:17:01ZengMDPI AGPathogens2076-08172022-11-011111128110.3390/pathogens11111281Tomography and Prognostic Indices in the State of the Art of Evaluation in Hospitalized Patients with COVID-19 PneumoniaSergio Críales-Vera0Huitzilihuitl Saucedo-Orozco1Pedro Iturralde-Torres2Gustavo Martínez-Mota3Estefanía Dávila-Medina4Verónica Guarner-Lans5Linaloe Manzano-Pech6Israel Pérez-Torres7María Elena Soto8Department of Computed Tomography, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano 1, Col. Sección XVI, Del. Tlalpan, Mexico City 14080, MexicoCardioneumology Department, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano 1, Col. Sección XVI, Del. Tlalpan, Mexico City 14080, MexicoInstituto Nacional de Cardiología Ignacio Chávez, Juan Badiano 1, Col. Sección XVI, Del. Tlalpan, Mexico City 14080, MexicoDepartment of Computed Tomography, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano 1, Col. Sección XVI, Del. Tlalpan, Mexico City 14080, MexicoDepartment of Computed Tomography, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano 1, Col. Sección XVI, Del. Tlalpan, Mexico City 14080, MexicoDepartment of Physiology, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano 1, Col. Sección XVI, Del. Tlalpan, Mexico City 14080, MexicoDepartment of Cardiovascular Biomedicine, Instituto Nacional de Cardiologíaa Ignacio Chávez, Juan Badiano 1, Col. Sección XVI, Del. Tlalpan, Mexico City 14080, MexicoDepartment of Cardiovascular Biomedicine, Instituto Nacional de Cardiologíaa Ignacio Chávez, Juan Badiano 1, Col. Sección XVI, Del. Tlalpan, Mexico City 14080, MexicoDepartment of Immunology, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano 1, Col. Sección XVI, Del. Tlalpan, Mexico City 14080, MexicoEvaluation in medical emergencies of COVID-19 patients represents a challenge to regulate preventive and timely management. There are key imaging and laboratory tools to classify the severity. The aim of the study was to evaluate the chest CT score performance and prognostic indices in COVID-19 patients to predict the progression to critical illness. This was a retrospective study between run between April and December 2020, in which 109 patients were included. Patients of any age and gender and who required hospitalization due to a confirmed COVID-19 diagnosis by RT-PCR and chest CT and laboratory were analyzed. In 75% of them, there was at least one comorbidity, and 30% developed critical illness, and the average mortality was 10%. In 49.5%, there was a CORADS-5 on admission, and in 50%, there was a peripheral distribution of the interstitial infiltrate in the left lower lobe. The risk factors were FiO<sub>2</sub>, CT score > 18, and the NRL index. The combination of the high-risk Quick COVID-19 Severity Index (qCSI) plus CT score > 18 indices was the best prediction index for the development of a critical condition. The combined use of indices in infected COVID-19 patients showed diagnostic accuracy and predicted severity. Imaging and the laboratory tests are key tools independent of the wave of recurrence.https://www.mdpi.com/2076-0817/11/11/1281chest tomographycombined indexesCOVID-19classification of severity |
| spellingShingle | Sergio Críales-Vera Huitzilihuitl Saucedo-Orozco Pedro Iturralde-Torres Gustavo Martínez-Mota Estefanía Dávila-Medina Verónica Guarner-Lans Linaloe Manzano-Pech Israel Pérez-Torres María Elena Soto Tomography and Prognostic Indices in the State of the Art of Evaluation in Hospitalized Patients with COVID-19 Pneumonia Pathogens chest tomography combined indexes COVID-19 classification of severity |
| title | Tomography and Prognostic Indices in the State of the Art of Evaluation in Hospitalized Patients with COVID-19 Pneumonia |
| title_full | Tomography and Prognostic Indices in the State of the Art of Evaluation in Hospitalized Patients with COVID-19 Pneumonia |
| title_fullStr | Tomography and Prognostic Indices in the State of the Art of Evaluation in Hospitalized Patients with COVID-19 Pneumonia |
| title_full_unstemmed | Tomography and Prognostic Indices in the State of the Art of Evaluation in Hospitalized Patients with COVID-19 Pneumonia |
| title_short | Tomography and Prognostic Indices in the State of the Art of Evaluation in Hospitalized Patients with COVID-19 Pneumonia |
| title_sort | tomography and prognostic indices in the state of the art of evaluation in hospitalized patients with covid 19 pneumonia |
| topic | chest tomography combined indexes COVID-19 classification of severity |
| url | https://www.mdpi.com/2076-0817/11/11/1281 |
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