Long-Acting Risperidone Dual Control System: Preparation, Characterization and Evaluation In Vitro and In Vivo

Long-Acting Risperidone Dual Control System: Preparation, Characterization and Evaluation In Vitro and In Vivo

Schizophrenia, a psychiatric disorder, requires long-term treatment; however, large fluctuations in blood drug concentration increase the risk of adverse reactions. We prepared a long-term risperidone (RIS) implantation system that can stabilize RIS release and established in-vitro and in-vivo evalu...

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Bibliographic Details
Main Authors: Xieguo Yan, Shiqiang Wang, Kaoxiang Sun
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Pharmaceutics
Subjects:
risperidone
microsphere
tablet
implant
sustained-release
stepwise regression
Online Access:https://www.mdpi.com/1999-4923/13/8/1210

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