COVID-19 Impact and Vaccination Willingness among Romanian Patients with Autoimmune/Immune-Mediated Diseases
Background: During the COVID-19 pandemic, patients with immune diseases are a vulnerable population. We aimed to evaluate their access to medical care, as well as their awareness and willingness to obtain the vaccine after a year of the SARS-CoV-2 pandemic. Methods: A cross-sectional, multicenter st...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-12-01
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| Series: | Healthcare |
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| Online Access: | https://www.mdpi.com/2227-9032/9/12/1707 |
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| author | Larisa Pinte Simona Caraiola Daniel Vasile Balaban Camelia Badea Diana Mazilu Georgeta Daniela Ionescu Maria-Ilinca Iosub Elena-Sabina Bălan Florentina Negoi Bianca Dumitrescu Bogdan Mateescu Ruxandra Ionescu Magda Ileana Parvu Cristian Baicus |
| author_facet | Larisa Pinte Simona Caraiola Daniel Vasile Balaban Camelia Badea Diana Mazilu Georgeta Daniela Ionescu Maria-Ilinca Iosub Elena-Sabina Bălan Florentina Negoi Bianca Dumitrescu Bogdan Mateescu Ruxandra Ionescu Magda Ileana Parvu Cristian Baicus |
| author_sort | Larisa Pinte |
| collection | DOAJ |
| description | Background: During the COVID-19 pandemic, patients with immune diseases are a vulnerable population. We aimed to evaluate their access to medical care, as well as their awareness and willingness to obtain the vaccine after a year of the SARS-CoV-2 pandemic. Methods: A cross-sectional, multicenter study was conducted on a questionnaire basis, handled both online as well as in person. Results: 651 patients with autoimmune or immune mediated diseases were enrolled. More than half (339/641 [53%]) reported difficulties in obtaining medical care throughout the pandemic and 135/651 ([21%]) of them were confirmed with COVID-19; 442/651, ([68%]) expressed their willingness to be vaccinated against SARS-CoV-2. The factors associated with an increased probability of vaccination were the male gender (OR = 2.01, CI95% 1.2–3.7, <i>p</i> = 0.001), the patient’s opinion that she/he was well informed (OR = 3.2, CI 95% 2.1–6.01, <i>p</i> < 0.001), physician’s advice (OR = 2.1, CI 95% 1.3–3.5, <i>p</i> < 0.001), and flu vaccination in the past (OR = 1.5, CI 95% 1.1–2.3, <i>p</i> < 0.001), while those associated with a decreased probability of vaccination were COVID-19 disease in the past medical history (OR = 0.7, CI 95% 0.3-0.95, <i>p</i> = 0.02), and the opinion that patients with autoimmune diseases are at increased risk for adverse reactions (OR = 0.7, CI95% 0.53–0.89, <i>p</i> = 0.001). Conclusions: Given the fact that considering themselves informed regarding vaccination is the most important factor in order to be immunized against SARS-CoV-2, effective information campaigns would substantially increase willingness. |
| first_indexed | 2024-03-10T04:00:35Z |
| format | Article |
| id | doaj.art-8b5dd78ed1064cd5b2e19dc272566bd5 |
| institution | Directory Open Access Journal |
| issn | 2227-9032 |
| language | English |
| last_indexed | 2024-03-10T04:00:35Z |
| publishDate | 2021-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Healthcare |
| spelling | doaj.art-8b5dd78ed1064cd5b2e19dc272566bd52023-11-23T08:34:27ZengMDPI AGHealthcare2227-90322021-12-01912170710.3390/healthcare9121707COVID-19 Impact and Vaccination Willingness among Romanian Patients with Autoimmune/Immune-Mediated DiseasesLarisa Pinte0Simona Caraiola1Daniel Vasile Balaban2Camelia Badea3Diana Mazilu4Georgeta Daniela Ionescu5Maria-Ilinca Iosub6Elena-Sabina Bălan7Florentina Negoi8Bianca Dumitrescu9Bogdan Mateescu10Ruxandra Ionescu11Magda Ileana Parvu12Cristian Baicus13Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, RomaniaFaculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, RomaniaFaculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, RomaniaFaculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, RomaniaFaculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, RomaniaInternal Medicine, Rheumatology and Gastroenterology Departments, Colentina Clinical Hospital, 072202 Bucharest, RomaniaInternal Medicine, Rheumatology and Gastroenterology Departments, Colentina Clinical Hospital, 072202 Bucharest, RomaniaInternal Medicine, Rheumatology and Gastroenterology Departments, Colentina Clinical Hospital, 072202 Bucharest, RomaniaInternal Medicine, Rheumatology and Gastroenterology Departments, Colentina Clinical Hospital, 072202 Bucharest, RomaniaFaculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, RomaniaFaculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, RomaniaFaculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, RomaniaInternal Medicine, Rheumatology and Gastroenterology Departments, Colentina Clinical Hospital, 072202 Bucharest, RomaniaFaculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, RomaniaBackground: During the COVID-19 pandemic, patients with immune diseases are a vulnerable population. We aimed to evaluate their access to medical care, as well as their awareness and willingness to obtain the vaccine after a year of the SARS-CoV-2 pandemic. Methods: A cross-sectional, multicenter study was conducted on a questionnaire basis, handled both online as well as in person. Results: 651 patients with autoimmune or immune mediated diseases were enrolled. More than half (339/641 [53%]) reported difficulties in obtaining medical care throughout the pandemic and 135/651 ([21%]) of them were confirmed with COVID-19; 442/651, ([68%]) expressed their willingness to be vaccinated against SARS-CoV-2. The factors associated with an increased probability of vaccination were the male gender (OR = 2.01, CI95% 1.2–3.7, <i>p</i> = 0.001), the patient’s opinion that she/he was well informed (OR = 3.2, CI 95% 2.1–6.01, <i>p</i> < 0.001), physician’s advice (OR = 2.1, CI 95% 1.3–3.5, <i>p</i> < 0.001), and flu vaccination in the past (OR = 1.5, CI 95% 1.1–2.3, <i>p</i> < 0.001), while those associated with a decreased probability of vaccination were COVID-19 disease in the past medical history (OR = 0.7, CI 95% 0.3-0.95, <i>p</i> = 0.02), and the opinion that patients with autoimmune diseases are at increased risk for adverse reactions (OR = 0.7, CI95% 0.53–0.89, <i>p</i> = 0.001). Conclusions: Given the fact that considering themselves informed regarding vaccination is the most important factor in order to be immunized against SARS-CoV-2, effective information campaigns would substantially increase willingness.https://www.mdpi.com/2227-9032/9/12/1707autoimmuneimmune mediatedrheumatic diseasesCOVID-19SARS-CoV2vaccine willingness |
| spellingShingle | Larisa Pinte Simona Caraiola Daniel Vasile Balaban Camelia Badea Diana Mazilu Georgeta Daniela Ionescu Maria-Ilinca Iosub Elena-Sabina Bălan Florentina Negoi Bianca Dumitrescu Bogdan Mateescu Ruxandra Ionescu Magda Ileana Parvu Cristian Baicus COVID-19 Impact and Vaccination Willingness among Romanian Patients with Autoimmune/Immune-Mediated Diseases Healthcare autoimmune immune mediated rheumatic diseases COVID-19 SARS-CoV2 vaccine willingness |
| title | COVID-19 Impact and Vaccination Willingness among Romanian Patients with Autoimmune/Immune-Mediated Diseases |
| title_full | COVID-19 Impact and Vaccination Willingness among Romanian Patients with Autoimmune/Immune-Mediated Diseases |
| title_fullStr | COVID-19 Impact and Vaccination Willingness among Romanian Patients with Autoimmune/Immune-Mediated Diseases |
| title_full_unstemmed | COVID-19 Impact and Vaccination Willingness among Romanian Patients with Autoimmune/Immune-Mediated Diseases |
| title_short | COVID-19 Impact and Vaccination Willingness among Romanian Patients with Autoimmune/Immune-Mediated Diseases |
| title_sort | covid 19 impact and vaccination willingness among romanian patients with autoimmune immune mediated diseases |
| topic | autoimmune immune mediated rheumatic diseases COVID-19 SARS-CoV2 vaccine willingness |
| url | https://www.mdpi.com/2227-9032/9/12/1707 |
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