Analytical and Clinical Assessment of a Portable, Isothermal Recombinase Polymerase Amplification (RPA) Assay for the Molecular Diagnosis of Urogenital Schistosomiasis

Analytical and Clinical Assessment of a Portable, Isothermal Recombinase Polymerase Amplification (RPA) Assay for the Molecular Diagnosis of Urogenital Schistosomiasis

Accurate diagnosis of urogenital schistosomiasis is crucial for disease surveillance and control. Routine diagnostic methods, however, lack sensitivity when assessing patients with low levels of infection still able to maintain pathogen transmission. Therefore, there is a need for highly sensitive d...

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Bibliographic Details
Main Authors: John Archer, Rebecca Barksby, Tom Pennance, Penelope Rostron, Faki Bakar, Stefanie Knopp, Fiona Allan, Fatma Kabole, Said M. Ali, Shaali M. Ame, David Rollinson, Bonnie L. Webster
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Molecules
Subjects:
urogenital schistosomiasis
<i>Schistosoma haematobium</i> (<i>S. haematobium</i>)
point-of-care
diagnosis
recombinase polymerase amplification (RPA)
control
Online Access:https://www.mdpi.com/1420-3049/25/18/4175

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