Mast cells and eosinophilic granule cells in Oncorhynchus mykiss: Are they similar or different?
Mast cells are important in inflammatory processes and in the nonspecific immune response, and there are also indications that these cells are associated with the effectors of the specific immune response. Eosinophilic granular cells are frequently compared to mast cells, and some authors maintain t...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-12-01
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| Series: | Fish and Shellfish Immunology Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667011921000244 |
| _version_ | 1819100260116463616 |
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| author | Luis Alberto Romano Fernando Pablo Silva Oliveira Virgínia Fonseca Pedrosa |
| author_facet | Luis Alberto Romano Fernando Pablo Silva Oliveira Virgínia Fonseca Pedrosa |
| author_sort | Luis Alberto Romano |
| collection | DOAJ |
| description | Mast cells are important in inflammatory processes and in the nonspecific immune response, and there are also indications that these cells are associated with the effectors of the specific immune response. Eosinophilic granular cells are frequently compared to mast cells, and some authors maintain that they are the same cells. In this study, we take a fresh look at the similarities and differences between these two cell types in Oncorhynchus mykiss. We evaluated the cytomorphology of each cell type with optical microscopy, their staining affinities, and their ultrastructure. We observed that mast cells were positive for CD117 (c-kit), while eosinophilic granular cells were negative for this marker. We propose that these two cell types have certain common characteristics but represent well-differentiated populations distributed in several Oncorhynchus mykiss tissues. |
| first_indexed | 2024-12-22T00:59:57Z |
| format | Article |
| id | doaj.art-8b66799e970940cd89ebc950d7d02268 |
| institution | Directory Open Access Journal |
| issn | 2667-0119 |
| language | English |
| last_indexed | 2024-12-22T00:59:57Z |
| publishDate | 2021-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Fish and Shellfish Immunology Reports |
| spelling | doaj.art-8b66799e970940cd89ebc950d7d022682022-12-21T18:44:13ZengElsevierFish and Shellfish Immunology Reports2667-01192021-12-012100029Mast cells and eosinophilic granule cells in Oncorhynchus mykiss: Are they similar or different?Luis Alberto Romano0Fernando Pablo Silva Oliveira1Virgínia Fonseca Pedrosa2Laboratory of Immunology and Pathology of Aquatic Organisms, Institute of Oceanography, Federal University of Rio Grande, 96210030, Rio Grande, Brazil; Corresponding author at: Instituto de Oceanografia, Universidade Federal do Rio Grande, 96210-030 Rio Grande do Sul, Brazil.Laboratory of Immunology and Pathology of Aquatic Organisms, Institute of Oceanography, Federal University of Rio Grande, 96210030, Rio Grande, BrazilLaboratory of Immunology and Pathology of Aquatic Organisms, Institute of Oceanography, Federal University of Rio Grande, 96210030, Rio Grande, BrazilMast cells are important in inflammatory processes and in the nonspecific immune response, and there are also indications that these cells are associated with the effectors of the specific immune response. Eosinophilic granular cells are frequently compared to mast cells, and some authors maintain that they are the same cells. In this study, we take a fresh look at the similarities and differences between these two cell types in Oncorhynchus mykiss. We evaluated the cytomorphology of each cell type with optical microscopy, their staining affinities, and their ultrastructure. We observed that mast cells were positive for CD117 (c-kit), while eosinophilic granular cells were negative for this marker. We propose that these two cell types have certain common characteristics but represent well-differentiated populations distributed in several Oncorhynchus mykiss tissues.http://www.sciencedirect.com/science/article/pii/S2667011921000244Eosinophilic granular cellsMast cellsImmunohistochemistryOncorhynchus mykissImmune response |
| spellingShingle | Luis Alberto Romano Fernando Pablo Silva Oliveira Virgínia Fonseca Pedrosa Mast cells and eosinophilic granule cells in Oncorhynchus mykiss: Are they similar or different? Fish and Shellfish Immunology Reports Eosinophilic granular cells Mast cells Immunohistochemistry Oncorhynchus mykiss Immune response |
| title | Mast cells and eosinophilic granule cells in Oncorhynchus mykiss: Are they similar or different? |
| title_full | Mast cells and eosinophilic granule cells in Oncorhynchus mykiss: Are they similar or different? |
| title_fullStr | Mast cells and eosinophilic granule cells in Oncorhynchus mykiss: Are they similar or different? |
| title_full_unstemmed | Mast cells and eosinophilic granule cells in Oncorhynchus mykiss: Are they similar or different? |
| title_short | Mast cells and eosinophilic granule cells in Oncorhynchus mykiss: Are they similar or different? |
| title_sort | mast cells and eosinophilic granule cells in oncorhynchus mykiss are they similar or different |
| topic | Eosinophilic granular cells Mast cells Immunohistochemistry Oncorhynchus mykiss Immune response |
| url | http://www.sciencedirect.com/science/article/pii/S2667011921000244 |
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