Differential expression of interferon responsive genes in rodent models of transmissible spongiform encephalopathy disease
<p>Abstract</p> <p>Background</p> <p>The pathological hallmarks of transmissible spongiform encephalopathy (TSE) diseases are the deposition of a misfolded form of a host-encoded protein (PrP<sup>res</sup>), marked astrocytosis, microglial activation and spo...
Main Authors: | Lazar Jozef, LeMaistre Jillian, Simon Sharon LR, Parchaliuk Debra, Stobart Michael J, Rubenstein Richard, Knox J David |
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Format: | Article |
Language: | English |
Published: |
BMC
2007-03-01
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Series: | Molecular Neurodegeneration |
Online Access: | http://www.molecularneurodegeneration.com/content/2/1/5 |
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