A Bitter Taste Receptor as a Novel Molecular Target on Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma
Cancer-associated fibroblasts (CAFs) execute diverse and complex functions in cancer progression. While reprogramming the crosstalk between CAFs and cancer epithelial cells is a promising avenue to evade the adverse effects of stromal depletion, drugs are limited by their suboptimal pharmacokinetics...
Main Authors: | Jessica Hung, Samantha M. Perez, Siva Sai Krishna Dasa, Sarah P. Hall, Danielle B. Heckert, Brian P. Murphy, Howard C. Crawford, Kimberly A. Kelly, Lindsey T. Brinton |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-03-01
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Series: | Pharmaceuticals |
Subjects: | |
Online Access: | https://www.mdpi.com/1424-8247/16/3/389 |
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