Systems-Level Mapping of Cancer Testis Antigen 1b/a to Sarcoma Pathways Identifies Activated Ran Binding-2 E3 SUMO-Protein Ligase and Transducin-Like Enhancer Protein 1

Systems-Level Mapping of Cancer Testis Antigen 1b/a to Sarcoma Pathways Identifies Activated Ran Binding-2 E3 SUMO-Protein Ligase and Transducin-Like Enhancer Protein 1

Here we describe the identification of genes and their encoded proteins that are expressed in advanced grade tumors by reconstruction of a sarcoma cancer testis gene 1b/a (catg1b/a) network. CTAG1B/A is an ortholog of the yeast/Drosophila transcription factor Pcc1p, and a member of the KEOPS transcr...

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Bibliographic Details
Main Authors: Nikolaos A. Papanikolaou, Prodromos Hytiroglou, Pavlina Pantelidou, Athanasios G. Papavassiliou, Lloyd L. Old
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Genetics
Subjects:
CtaG
GSEA
network
sarcoma
RanBP2
TLE1
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.834445/full

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