A rare case of long‐term survival from metachronous bilateral adrenal metastasis of lung adenocarcinoma after combined surgical removal and immunochemotherapy
Introduction The prognosis of adrenal metastasis from non‐small cell lung cancer is very poor. A recent report described the efficacy of the surgical removal of adrenal metastasis when solitary. However, metachronous bilateral adrenal metastasis is extremely rare, and a treatment strategy has not be...
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| Format: | Article |
| Language: | English |
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Wiley
2022-11-01
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| Series: | IJU Case Reports |
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| Online Access: | https://doi.org/10.1002/iju5.12519 |
| _version_ | 1797989252826398720 |
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| author | Nami Tomiyama Taku Naiki Aya Naiki‐Ito Tatsuya Kawai Toshiki Etani Masakazu Gonda Maria Aoki Toshiharu Morikawa Yosuke Sugiyama Takahiro Yasui |
| author_facet | Nami Tomiyama Taku Naiki Aya Naiki‐Ito Tatsuya Kawai Toshiki Etani Masakazu Gonda Maria Aoki Toshiharu Morikawa Yosuke Sugiyama Takahiro Yasui |
| author_sort | Nami Tomiyama |
| collection | DOAJ |
| description | Introduction The prognosis of adrenal metastasis from non‐small cell lung cancer is very poor. A recent report described the efficacy of the surgical removal of adrenal metastasis when solitary. However, metachronous bilateral adrenal metastasis is extremely rare, and a treatment strategy has not been established. Case presentation Herein, we describe a 52‐year‐old Asian male who presented with a right adrenal metastasis of non‐small cell lung cancer 8 months after immunochemotherapy and surgical resection of the lung. He underwent combined systemic treatment and a laparoscopic right adrenalectomy; however, after 9 months, a metachronous left adrenal metastasis emerged. A subsequent laparoscopic left adrenalectomy and systemic treatment led to long‐term progression‐free survival. Conclusion The appropriate surgical indication and combined systemic treatment of a metachronous bilateral adrenal metastasis in non‐small cell lung cancer may extend the prognosis. |
| first_indexed | 2024-04-11T08:16:05Z |
| format | Article |
| id | doaj.art-8b6b1ba295d148a0aba3b96a1cb39837 |
| institution | Directory Open Access Journal |
| issn | 2577-171X |
| language | English |
| last_indexed | 2024-04-11T08:16:05Z |
| publishDate | 2022-11-01 |
| publisher | Wiley |
| record_format | Article |
| series | IJU Case Reports |
| spelling | doaj.art-8b6b1ba295d148a0aba3b96a1cb398372022-12-22T04:35:09ZengWileyIJU Case Reports2577-171X2022-11-015647447810.1002/iju5.12519A rare case of long‐term survival from metachronous bilateral adrenal metastasis of lung adenocarcinoma after combined surgical removal and immunochemotherapyNami Tomiyama0Taku Naiki1Aya Naiki‐Ito2Tatsuya Kawai3Toshiki Etani4Masakazu Gonda5Maria Aoki6Toshiharu Morikawa7Yosuke Sugiyama8Takahiro Yasui9Department of Nephro‐urology Nagoya City University, Graduate School of Medical Sciences Nagoya JapanDepartment of Nephro‐urology Nagoya City University, Graduate School of Medical Sciences Nagoya JapanDepartment of Experimental Pathology and Tumor Biology Nagoya City University, Graduate School of Medical Sciences Nagoya JapanDeparetment of Radiology Nagoya City University, Graduate School of Medical Sciences Nagoya JapanDepartment of Nephro‐urology Nagoya City University, Graduate School of Medical Sciences Nagoya JapanDepartment of Nephro‐urology Nagoya City University, Graduate School of Medical Sciences Nagoya JapanDepartment of Nephro‐urology Nagoya City University, Graduate School of Medical Sciences Nagoya JapanDepartment of Nephro‐urology Nagoya City University, Graduate School of Medical Sciences Nagoya JapanDepartment of Pharmacy Nagoya City University Hospital Nagoya JapanDepartment of Nephro‐urology Nagoya City University, Graduate School of Medical Sciences Nagoya JapanIntroduction The prognosis of adrenal metastasis from non‐small cell lung cancer is very poor. A recent report described the efficacy of the surgical removal of adrenal metastasis when solitary. However, metachronous bilateral adrenal metastasis is extremely rare, and a treatment strategy has not been established. Case presentation Herein, we describe a 52‐year‐old Asian male who presented with a right adrenal metastasis of non‐small cell lung cancer 8 months after immunochemotherapy and surgical resection of the lung. He underwent combined systemic treatment and a laparoscopic right adrenalectomy; however, after 9 months, a metachronous left adrenal metastasis emerged. A subsequent laparoscopic left adrenalectomy and systemic treatment led to long‐term progression‐free survival. Conclusion The appropriate surgical indication and combined systemic treatment of a metachronous bilateral adrenal metastasis in non‐small cell lung cancer may extend the prognosis.https://doi.org/10.1002/iju5.12519adrenalectomylong‐term survivallung adenocarcinomametachronous bilateral adrenal metastasis |
| spellingShingle | Nami Tomiyama Taku Naiki Aya Naiki‐Ito Tatsuya Kawai Toshiki Etani Masakazu Gonda Maria Aoki Toshiharu Morikawa Yosuke Sugiyama Takahiro Yasui A rare case of long‐term survival from metachronous bilateral adrenal metastasis of lung adenocarcinoma after combined surgical removal and immunochemotherapy IJU Case Reports adrenalectomy long‐term survival lung adenocarcinoma metachronous bilateral adrenal metastasis |
| title | A rare case of long‐term survival from metachronous bilateral adrenal metastasis of lung adenocarcinoma after combined surgical removal and immunochemotherapy |
| title_full | A rare case of long‐term survival from metachronous bilateral adrenal metastasis of lung adenocarcinoma after combined surgical removal and immunochemotherapy |
| title_fullStr | A rare case of long‐term survival from metachronous bilateral adrenal metastasis of lung adenocarcinoma after combined surgical removal and immunochemotherapy |
| title_full_unstemmed | A rare case of long‐term survival from metachronous bilateral adrenal metastasis of lung adenocarcinoma after combined surgical removal and immunochemotherapy |
| title_short | A rare case of long‐term survival from metachronous bilateral adrenal metastasis of lung adenocarcinoma after combined surgical removal and immunochemotherapy |
| title_sort | rare case of long term survival from metachronous bilateral adrenal metastasis of lung adenocarcinoma after combined surgical removal and immunochemotherapy |
| topic | adrenalectomy long‐term survival lung adenocarcinoma metachronous bilateral adrenal metastasis |
| url | https://doi.org/10.1002/iju5.12519 |
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