Knockout of VDAC1 in H9c2 Cells Promotes Oxidative Stress-Induced Cell Apoptosis through Decreased Mitochondrial Hexokinase II Binding and Enhanced Glycolytic Stress
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Cell Physiol Biochem Press GmbH & Co KG
2020-09-01
|
Series: | Cellular Physiology and Biochemistry |
Online Access: | https://www.cellphysiolbiochem.com/Articles/000274/ |
_version_ | 1818112888776163328 |
---|---|
author | Meiying Yang Jie Sun David F. Stowe Emad Tajkhorshid Wai-Meng Kwok Amadou K. S. Camara |
author_facet | Meiying Yang Jie Sun David F. Stowe Emad Tajkhorshid Wai-Meng Kwok Amadou K. S. Camara |
author_sort | Meiying Yang |
collection | DOAJ |
first_indexed | 2024-12-11T03:26:06Z |
format | Article |
id | doaj.art-8b759b52b15a48f99ef5c8919dfe77ea |
institution | Directory Open Access Journal |
issn | 1015-8987 |
language | English |
last_indexed | 2024-12-11T03:26:06Z |
publishDate | 2020-09-01 |
publisher | Cell Physiol Biochem Press GmbH & Co KG |
record_format | Article |
series | Cellular Physiology and Biochemistry |
spelling | doaj.art-8b759b52b15a48f99ef5c8919dfe77ea2022-12-22T01:22:30ZengCell Physiol Biochem Press GmbH & Co KGCellular Physiology and Biochemistry1015-89872020-09-0154585387410.33594/000000274Knockout of VDAC1 in H9c2 Cells Promotes Oxidative Stress-Induced Cell Apoptosis through Decreased Mitochondrial Hexokinase II Binding and Enhanced Glycolytic StressMeiying Yang0Jie Sun1 David F. Stowe2Emad Tajkhorshid3Wai-Meng Kwok4Amadou K. S. Camara5Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, USADepartment of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, USA; Institute of Clinical Medicine Research, Department of Gastroenterology and Hepatology, Suzhou Hospital affiliated with Nanjing Medical University, Suzhou, Jiangsu, ChinaDepartment of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, USA; Research Service, Zablocki VA Medical Center, Milwaukee, WI, USA; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI, USA; Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI, USANIH Center for Macromolecular Modeling and Bioinformatics, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana Champaign, Urbana, IL, USA; Department of Biochemistry, and Center for Biophysics and Quantitative Biology, University of Illinois at Urbana Champaign, Urbana, IL, USADepartment of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, USA; Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI, USA; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA; Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, WI, USADepartment of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, USA; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI, USA; Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI, USA; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USAhttps://www.cellphysiolbiochem.com/Articles/000274/ |
spellingShingle | Meiying Yang Jie Sun David F. Stowe Emad Tajkhorshid Wai-Meng Kwok Amadou K. S. Camara Knockout of VDAC1 in H9c2 Cells Promotes Oxidative Stress-Induced Cell Apoptosis through Decreased Mitochondrial Hexokinase II Binding and Enhanced Glycolytic Stress Cellular Physiology and Biochemistry |
title | Knockout of VDAC1 in H9c2 Cells Promotes Oxidative Stress-Induced Cell Apoptosis through Decreased Mitochondrial Hexokinase II Binding and Enhanced Glycolytic Stress |
title_full | Knockout of VDAC1 in H9c2 Cells Promotes Oxidative Stress-Induced Cell Apoptosis through Decreased Mitochondrial Hexokinase II Binding and Enhanced Glycolytic Stress |
title_fullStr | Knockout of VDAC1 in H9c2 Cells Promotes Oxidative Stress-Induced Cell Apoptosis through Decreased Mitochondrial Hexokinase II Binding and Enhanced Glycolytic Stress |
title_full_unstemmed | Knockout of VDAC1 in H9c2 Cells Promotes Oxidative Stress-Induced Cell Apoptosis through Decreased Mitochondrial Hexokinase II Binding and Enhanced Glycolytic Stress |
title_short | Knockout of VDAC1 in H9c2 Cells Promotes Oxidative Stress-Induced Cell Apoptosis through Decreased Mitochondrial Hexokinase II Binding and Enhanced Glycolytic Stress |
title_sort | knockout of vdac1 in h9c2 cells promotes oxidative stress induced cell apoptosis through decreased mitochondrial hexokinase ii binding and enhanced glycolytic stress |
url | https://www.cellphysiolbiochem.com/Articles/000274/ |
work_keys_str_mv | AT meiyingyang knockoutofvdac1inh9c2cellspromotesoxidativestressinducedcellapoptosisthroughdecreasedmitochondrialhexokinaseiibindingandenhancedglycolyticstress AT jiesun knockoutofvdac1inh9c2cellspromotesoxidativestressinducedcellapoptosisthroughdecreasedmitochondrialhexokinaseiibindingandenhancedglycolyticstress AT davidfstowe knockoutofvdac1inh9c2cellspromotesoxidativestressinducedcellapoptosisthroughdecreasedmitochondrialhexokinaseiibindingandenhancedglycolyticstress AT emadtajkhorshid knockoutofvdac1inh9c2cellspromotesoxidativestressinducedcellapoptosisthroughdecreasedmitochondrialhexokinaseiibindingandenhancedglycolyticstress AT waimengkwok knockoutofvdac1inh9c2cellspromotesoxidativestressinducedcellapoptosisthroughdecreasedmitochondrialhexokinaseiibindingandenhancedglycolyticstress AT amadoukscamara knockoutofvdac1inh9c2cellspromotesoxidativestressinducedcellapoptosisthroughdecreasedmitochondrialhexokinaseiibindingandenhancedglycolyticstress |