Associations of Estimated Pulse Wave Velocity with Body Mass Index and Waist Circumference among General Korean Adults
The correlation between body fat parameters and arterial stiffness is still under debate. This study aimed to examine the associations of body mass index (BMI) and waist circumference (WC) with estimated pulse wave velocity (ePWV). We utilized data from 14,228 subjects (mean age 53.4 ± 16.8 years; 5...
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MDPI AG
2023-10-01
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| Series: | Metabolites |
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| Online Access: | https://www.mdpi.com/2218-1989/13/10/1082 |
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| author | Hack-Lyoung Kim Hyun Sung Joh Woo-Hyun Lim Jae-Bin Seo Sang-Hyun Kim Joo-Hee Zo Myung-A Kim |
| author_facet | Hack-Lyoung Kim Hyun Sung Joh Woo-Hyun Lim Jae-Bin Seo Sang-Hyun Kim Joo-Hee Zo Myung-A Kim |
| author_sort | Hack-Lyoung Kim |
| collection | DOAJ |
| description | The correlation between body fat parameters and arterial stiffness is still under debate. This study aimed to examine the associations of body mass index (BMI) and waist circumference (WC) with estimated pulse wave velocity (ePWV). We utilized data from 14,228 subjects (mean age 53.4 ± 16.8 years; 56.9% were female) from the Korean National Health and Nutrition Examination Survey. The ePWV was calculated using a formula based on age and blood pressure. Simple linear correlation analyses revealed significant associations between both BMI and ePWV (<i>r</i> = 0.098; <i>p</i> < 0.001) and WC and ePWV (<i>r</i> = 0.291; <i>p</i> < 0.001), with a stronger correlation observed between WC and ePWV. Multiple linear regression analysis demonstrated that WC remained significantly associated with ePWV after adjusting for potential confounders (<i>β</i> = 0.020; <i>p</i> = 0.001). However, a statistically significant association was not found between BMI and ePWV (<i>β</i> = 0.011; <i>p</i> = 0.076). Multiple binary logistic regression analysis further indicated that both higher BMI and WC were independently associated with higher ePWV, but the association was more pronounced between WC and ePWV than between BMI and ePWV. These findings underscore a stronger correlation between visceral obesity (as indicated by WC) and arterial stiffness (as indicated by ePWV) compared to overall obesity (as indicated by BMI). This highlights the potential significance of abdominal obesity in assessing cardiovascular risk. |
| first_indexed | 2024-03-10T21:03:38Z |
| format | Article |
| id | doaj.art-8b7609afad784cceaf5eb9597304fe5e |
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| issn | 2218-1989 |
| language | English |
| last_indexed | 2024-03-10T21:03:38Z |
| publishDate | 2023-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Metabolites |
| spelling | doaj.art-8b7609afad784cceaf5eb9597304fe5e2023-11-19T17:20:14ZengMDPI AGMetabolites2218-19892023-10-011310108210.3390/metabo13101082Associations of Estimated Pulse Wave Velocity with Body Mass Index and Waist Circumference among General Korean AdultsHack-Lyoung Kim0Hyun Sung Joh1Woo-Hyun Lim2Jae-Bin Seo3Sang-Hyun Kim4Joo-Hee Zo5Myung-A Kim6Division of Cardiology, Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul National University College of Medicine, Seoul 07061, Republic of KoreaDivision of Cardiology, Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul National University College of Medicine, Seoul 07061, Republic of KoreaDivision of Cardiology, Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul National University College of Medicine, Seoul 07061, Republic of KoreaDivision of Cardiology, Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul National University College of Medicine, Seoul 07061, Republic of KoreaDivision of Cardiology, Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul National University College of Medicine, Seoul 07061, Republic of KoreaDivision of Cardiology, Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul National University College of Medicine, Seoul 07061, Republic of KoreaDivision of Cardiology, Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul National University College of Medicine, Seoul 07061, Republic of KoreaThe correlation between body fat parameters and arterial stiffness is still under debate. This study aimed to examine the associations of body mass index (BMI) and waist circumference (WC) with estimated pulse wave velocity (ePWV). We utilized data from 14,228 subjects (mean age 53.4 ± 16.8 years; 56.9% were female) from the Korean National Health and Nutrition Examination Survey. The ePWV was calculated using a formula based on age and blood pressure. Simple linear correlation analyses revealed significant associations between both BMI and ePWV (<i>r</i> = 0.098; <i>p</i> < 0.001) and WC and ePWV (<i>r</i> = 0.291; <i>p</i> < 0.001), with a stronger correlation observed between WC and ePWV. Multiple linear regression analysis demonstrated that WC remained significantly associated with ePWV after adjusting for potential confounders (<i>β</i> = 0.020; <i>p</i> = 0.001). However, a statistically significant association was not found between BMI and ePWV (<i>β</i> = 0.011; <i>p</i> = 0.076). Multiple binary logistic regression analysis further indicated that both higher BMI and WC were independently associated with higher ePWV, but the association was more pronounced between WC and ePWV than between BMI and ePWV. These findings underscore a stronger correlation between visceral obesity (as indicated by WC) and arterial stiffness (as indicated by ePWV) compared to overall obesity (as indicated by BMI). This highlights the potential significance of abdominal obesity in assessing cardiovascular risk.https://www.mdpi.com/2218-1989/13/10/1082arterial stiffnessbody mass indexpulse wave velocityobesitywaist circumference |
| spellingShingle | Hack-Lyoung Kim Hyun Sung Joh Woo-Hyun Lim Jae-Bin Seo Sang-Hyun Kim Joo-Hee Zo Myung-A Kim Associations of Estimated Pulse Wave Velocity with Body Mass Index and Waist Circumference among General Korean Adults Metabolites arterial stiffness body mass index pulse wave velocity obesity waist circumference |
| title | Associations of Estimated Pulse Wave Velocity with Body Mass Index and Waist Circumference among General Korean Adults |
| title_full | Associations of Estimated Pulse Wave Velocity with Body Mass Index and Waist Circumference among General Korean Adults |
| title_fullStr | Associations of Estimated Pulse Wave Velocity with Body Mass Index and Waist Circumference among General Korean Adults |
| title_full_unstemmed | Associations of Estimated Pulse Wave Velocity with Body Mass Index and Waist Circumference among General Korean Adults |
| title_short | Associations of Estimated Pulse Wave Velocity with Body Mass Index and Waist Circumference among General Korean Adults |
| title_sort | associations of estimated pulse wave velocity with body mass index and waist circumference among general korean adults |
| topic | arterial stiffness body mass index pulse wave velocity obesity waist circumference |
| url | https://www.mdpi.com/2218-1989/13/10/1082 |
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